#cilastatin

[er-cryptid]

Cilastatin

Names -- Primaxin

Class -- anti-infective -- carbapenems

Use -- treatment of lower respiratory tract infections -- treatment of urinary tract infections -- treatment of abdominal infections -- treatment of gynecologic infections -- treatment of skin infections -- treatment of skin structure infections -- treatment of bone infections -- treatment of joint infections -- treatment of bacteremia -- treatment of endocarditis -- treatment of polymicrobid infections -- treatment of infections with resistant organisms

Action -- binds to bacterial cell wall, resulting in cell death -- broad-spectrum against gram-positive and gram-negative aerobes and anaerobes

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[worldwide-research-reports]

Imipenem-Cilastatin current market size is 5446.69 Million USD, with a CAGR of 17% for the session 2014-2017 and it is forecasted to grow with a CAGR of 23% during the session of 2018-2023.

"Imipenem/Cilastatin" is a combination drug consists of two individual drugs: Imipenem and Cilastatin Sodium in the ratio of 1:1 by weight. “Primaxin” the brand of Originator Merck & Co. contains Imipenem & Cilastatin, a new beta-lactam agent of the carbapenem class (1-Beta-methyl carbapenem). Primaxin is an antibiotic useful for the treatment of a number of bacterial infections. Imipenem/Cilastatin current market size is 5446.69 Million USD, with a CAGR of 17% for the session 2014-2017 & it is forecasted to grow with a CAGR of 23% during the session of 2018-2023. The multiple indications among all other carbapenem’s provide contribution in the market growth. 

Imipenem is a white or pale yellow powder & broad-spectrum beta-lactam antibiotic & Cilastatin sodium is light yellow hygroscopic, amorphous powder. "Imipenem/Cilastatin" is off white to yellowish white hygroscopic powder. For injection formulation it is available in two forms i.e. powder & solution. It is given by injection into a vein or muscle. Primaxin (Imipenem and Cilastatin for Injectable Suspension) is a formulation of Imipenem (a thienamycin antibiotic) and Cilastatin sodium (the inhibitor of the renal dipeptidase, dehydropeptidase-I).  Primaxin is a potent broad spectrum antibacterial agent for intramuscular administration.

[amcrasto]

Cilastatin, циластатин , سيلاستاتين , 西司他丁 ,

Cilastatin, циластатин , سيلاستاتين , 西司他丁 ,

Cilastatin

シラスタチン

циластатин [Russian] [INN] سيلاستاتين [Arabic] [INN] 西司他丁 [Chinese] [INN]

UNII141A6AMN38

CAS number 82009-34-5

WeightAverage: 358.453 Monoisotopic: 358.156242642

Chemical FormulaC16H26N2O5S

(L)-7-(2-Amino-2-carboxy-ethylsulfanyl)-2-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid

(Z)-(S)-6-carboxy-6-[(S)-2,2-dimethylcyclopropanecarboxamido]hex-5-enyl-L-cysteine

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[preventivehealthcare101-blog]

Cilastatin | Find why Cilastatin is prescribed including its typical usage, side effects and safety, interactions, warnings and ask a doctor for expert advise on Cilastatin at MediKlik.com

Cilastatin | Find why Cilastatin is prescribed including its typical usage, side effects and safety, interactions, warnings and ask a doctor for expert advise on Cilastatin at MediKlik.com