#fda 2019

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Fam-trastuzumab deruxtecan-nxki

Fam-trastuzumab deruxtecan-nxki FormulaC6460H9972N1724O2014S44. (C52H57FN9O13)8CAS1826843-81-5Mol weight153701.9811 Antineoplastic  DiseaseBreast cancer (HER2 positive) DS-8201a Trastuzumab deruxtecan, sold under the brand name Enhertu, is an antibody-drug conjugate consisting of the humanized monoclonal antibody trastuzumab (Herceptin) covalently linked to the topoisomerase I…

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Zanubrutinib, ザヌブルチニブ , занубрутиниб , زانوبروتينيب ,

Zanubrutinib, ザヌブルチニブ , занубрутиниб , زانوبروتينيب ,

Zanubrutinib, BGB-3111

Formula C27H29N5O3 CAS 1691249-45-2 Mol weight 471.5509

FDA , 2019/11/14, Brukinsa

ザヌブルチニブ ,

занубрутиниб [Russian] زانوبروتينيب [Arabic] (7S)-7-(1-Acryloyl-4-piperidinyl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide Pyrazolo[1,5-a]pyrimidine-3-carboxamide,…

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Brilliant blue G , ブリリアントブルーG ,

Brilliant blue G , ブリリアントブルーG ,

Brilliant blue G

FDA 2019, 12/20/2019, TISSUEBLUE, New Drug Application (NDA): 209569 Company: DUTCH OPHTHALMIC, PRIORITY; Orphan

OPQ recommends APPROVAL of NDA 209569 for commercialization of TissueBlue (Brilliant Blue G Ophthalmic Solution), 0.025%

Neuroprotectant

sodium;3-[[4-[[4-(4-ethoxyanilino)phenyl]-[4-[ethyl-[(3-sulfonatophenyl)methyl]azaniumylidene]-2-methylcyclohexa-2,5-dien-1-yliden…

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Fluorodopa F 18, フルオロドパ (18F), флуородопа (18F) , فلورودوبا (18F) , 氟[18F]多巴 ,

Fluorodopa F 18, フルオロドパ (18F), флуородопа (18F) , فلورودوبا (18F) , 氟[18F]多巴 ,

Fluorodopa F 18

2019/10/10, fda 2019,

Formula C9H10FNO4 Cas 92812-82-3 Mol weight 215.1784

Diagnostic aid (brain imaging), Radioactive agent, for use in positron emission tomography (PET)

CAS 92812-82-3

フルオロドパ (18F)

L-6-(18F)Fluoro-DOPA L-Tyrosine, 2-fluoro-18F-5-hydroxy- [ACD/Index Name] флуородопа (18F) [Russian] [INN] فلورودوبا (18F) [Arabic] [INN] 氟[18F]多巴 [Chinese] [INN]((1…

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Enfortumab vedotin

Enfortumab vedotin

Formula C6642H10284N1742O2063S46 Cas 1346452-25-2 Mol weight 149022.148

AGS-22M6E, enfortumab vedotin-ejfv

Fda approved 2019/12/18, Padcev

Antineoplastic, Nectin-4 antibody, Tubulin polymerization inhibitor, Urothelial cancer

エンホルツマブベドチン (遺伝子組換え);

protein Based Therapies, Monoclonal antibody, mAb, 

UNII DLE8519RWM

Immunoglobulin G1, anti-(human nectin-4)…

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Cefiderocol, セフィデロコル , цефидерокол , سيفيديروكول , 头孢德罗 ,

Cefiderocol, セフィデロコル , цефидерокол , سيفيديروكول , 头孢德罗 ,

Cefiderocol

セフィデロコル;

Formula C30H34ClN7O10S2 CAS 1225208-94-5 Mol weight 752.2149

Antibacterial, Cell wall biosynthesis inhibitor, enicillin binding protein, Siderophore cephalosporin

Fetroja (TN)

FDA, Cefiderocol, APPROVED, 2019/11/14

(6R,7R)-7-{[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-{[(2-carboxy-2-propanyl)oxy]imino}acetyl]amino}-3-[(1-{2-[(2-chloro-3,4-dihydroxybenzoyl)amino]et…

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Givosiran, ギボシラン ,

Givosiran

N-[1,3-bis[3-[3-[5-[(2R,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypentanoylamino]propylamino]-3-oxopropoxy]-2-[[3-[3-[5-[(2R,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypentanoylamino]propylamino]-3-oxopropoxy]methyl]propan-2-yl]-12-[(2R,4R)-4-hydroxy-2-methylpyrrolidin-1-yl]-12-oxododecanamide

Treatment of Acute Hepatic Porphyria…

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Golodirsen, ゴロジルセン;

Golodirsen

RNA, [P-deoxy-P-(dimethylamino)](2′,3′-dideoxy-2′,3′-imino-2′,3′-seco)(2’a→5′)(G-m5U-m5U-G-C-C-m5U-C-C-G-G-m5U-m5U-C-m5U-G-A-A-G-G-m5U-G-m5U-m5U-C), 5′-[P-[4-[[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]carbonyl]-1-piperazinyl]-N,N-dimethylphosphonamidate]

Nucleic Acid Sequence

Sequence Length: 25

Formula C305H481N138O112P25 CAS 1422959-91-8 Mol weight 8647.2841

Exon 53:…

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