I figure if I'm approaching openworm.org from cognitive science, philosophy, and architecture there may be others out there reading the blog for parallels with other directions and disciplines. I'm looking to biomimetic research in synthetic biology and AI for considerations of metabolic architecture derived from reformulating Alan Turing's question: "Can machines think?" (1950) into: can buildings think? (Dollens forthcoming 2014). Such a reformulation requires identifying architecture in the same phylum as machines. In this frame, the C. elegans, OpenWorm, 3D body already establishes a CAD architecture encasing performative systems. If further extrapolated OpenWorm's search for e-life may inform a synthetic vision of potential intelligent and/or metabolizing buildings. The benefit analogy in such a transformation (e-worm-to-building), resides in a potentially performative architecture simulation germane to domains of communication, materialization, computational architecture, bioremediation, and sustainability.
Related, Ezequiel Di Paolo's "Robotics Inspired in the Organism" (2010) generates discussion around intelligence, presence, environment, and "sense-making" via evolved autopoiesis (Di Paolo 2005. Maturana & Varela 1980. Weber & Varela 2002). With that mapping of autopoietic biological life, I think OpenWorm generates a way to envision a synthetic lifeform influencing intelligent architecture defined through theory but tested in virtual and generative models. Thereafter, I ask myself: why can't a building think? For example, Di Paolo reworks autopoiesis into the position of biologically supporting "sense-making" that, in turn, seems to me to be a link where discussion from OpenWorm may influence conceptual and theoretical modeling for metabolizing architectural systems. I think, simultaneous (OpenWorm-to-building) analogy and virtual-model comparison becomes thinkable as parallel experiments if the CAD worm body is considered stationary as a building would require, where skin/membrane functions manifest as a biological facade, and cognitive functions are seen addressing desired, programmed, and adaptive environmental remediation represented by the petri dish.