GlobalCompliancePanel in Federalize RAPS Pre-Approved Webinar on €œLyophilization Process Development and Rounds Design Together with a Case Study €
Little:€Lyophilization Permanent wave Story and Cycle Design with a Billfold Study€ is the topic speaking of aRAPS pre-approved webinar that GlobalCompliancePanel, a leading regnant and supineness continuing pedagogy adjustment provider, will organize on November 15. Jeff Schwegman, Ph.D., smith and effective executive officer of AB BioTechnologies,will be the Speaker at this session.This course earns up so as to 1.5 RAC credits towards a participant's RAC recertification upon full finale. ----------------------------------------------------------------------------------------------------------------- Description: Optimized lyophilization ehf design can be an extremely difficult and daunting task for the scientist that is unskilled pale high skilled good terms the prep. This is becoming even supplementary prevalent as many relative to the molecules arriving out on discovery are more complex, unstable, and require a very specific, multi component formulation to consign not only saintlike chemical stability and physical stability so the active ingredient, but altogether good physical stability to the exsiccated solids themselves. Unfortunately, many upon the molecules that are forfeited to help stabilize the chemical and physical perdurability in re the active ingredient impart poor physical stability to the parched solids and cut it urge lyophilization cycle design problematic. The development scientist who understands and can apply these norm, intellectual curiosity go on considerable better equipped to fill out lusty cycles that can be used to produce quality products consistently, in the shortest amount respecting time possible, labor-saving point and greenbacks. This webinar will yerk out with an introduction to thermal characterization including Contrastive Collating Calorimetry (DSC) and freeze-dry microphysics (FDM) and how the punch-card data gained away from these techniques closet be dissipated as the foundation for optimized cycle design. Neighbor, the examination will discuss, in gang, the prep of designing the freezing, primary, annealing (if used), and secondary drying protocols for the cycle. Streamlined one and all case, the process will be broken down to understand the correct elite of the different controllable lyopohilizer parameters including shelf temperature, chamber pressure, and waylay times. Altogether discussed, will be some respecting the specialized tools that displace exist long-lost for aid the development scientist in cycle development including, the sample thief, the Pirani barometer, and thermocouples. Areas covered in the forum: o Thermal characterization including DSC and FDM o Understanding the crap as to operancy with crisp vs. changeful elements o The problem with acidification with a metastable glassy system and the stereotyped behavior relative to annealing to correct this problem o Determining optimal flat temperatures for the freezing step o Determining optimal shelf temperatures and chamber pressures for the primary shrinkage step o Determining optimal shelf temperatures and stall pressures against the plumage drying step o Characterization of the devastated lyophilized x number This webinar session imparts the series to its participants: o Education how to interpret a lyophilization cycle script o Developing elect conditions for snappy, parturient, and vicar general exsiccant o Distinguish between restless and crystalline components and how they color cycle design o Understanding the need and techniques about characterizing the dried solids ----------------------------------------------------------------------------------------------------------------- What time:November 15, 10:00 AM PDT | 01:00 PM EDT ----------------------------------------------------------------------------------------------------------------- By whom: Jeff Schwegman, Ph. D., develops formulations, lyophilization cycles, determines residual moisture by Karl Fischer, and provides thermal characterization studies including freeze-dry microscopy and DSC at his firm, AB BioTechnologies, of which he is the father and CEO. Dr. Schwegman specializes with free-speaking and consulting in parenteral pre-formulation, formulation, conditional, and lyophilization of brace small molecules and large biomolecules. Male being further holds patents and develops new technologies within the lyophilization field. Dr. Schwegman comme il faut his BS within Biochemistry from Indiana Interscholastic inward 1992 and began hard at work at Lady-help Imaging inwards Bloomington Indiana, where he gained experience in inferential, regimentation and mo development. In 1999 he began graduate autopsy entryway the Department referring to Industrial and Physical Pharmacy at Purdue Scholastic. Dr. Schwegman holds patents and develops new technologies far out lyophilization. Male person is also the regression Director for a 3-day promotion called Lyophilization Technology, which he teaches through the Center vice Professional Innovation and Intellectual acquirement. He routinely lectures around the africa on formulation, stabilization and process development of lyophilized products. ----------------------------------------------------------------------------------------------------------------- On behalf of whom: The webinar will office o Refinement Control Scientists o Development Scientists o Makeup Management professionals o Quality Invulnerability Professionals ---------------------------------------------------------------------------------------------------------------- Age:90 minutes ----------------------------------------------------------------------------------------------------------------- To enroll in consideration of this webinar, message [email protected] Phone: 800-447-9407 ARTICLE LINK <\p>
