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Activating Cyclin A [Diagram]
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RNA Interference
Introduction RNAi was discovered by Andrew Fire and Craig Mello via an experiment on gene expression in Caenorhabditis elegans, in which they injected mRNA (also known as sense sequence) coding for muscle protein production showed no response form c. elegans. From this, they tried injecting anti-sense RNA to pair with sense mRNA, and yet no response was elicited. Eventually they chose to inject…
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