#data-terminal-unit

[inhandnetworks-blog]

Amazing H car router  ubble Image of Globular Cluster NGC 3201

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This image from the NASA/ESA Hubble Space Telescope reveals a glistening and ancient globular cluster named NGC 3201 — a gathering of hundreds of thousands of stars bound together bMV smart grid sensory gravity. NGC 3201 was discovered in 1826 by the Scottish astronomer James Dunlop, who described it as a “pretty large, pretty bright” object that becomes “rather irregular” towards its center.

Globular clusters are found around all large galaxies, but their origin and role in galaxy formation remain tantalisingly unclear. Astronomers recently discovered a black hole lurking at th Grid Analytics System  e heart of NGC 3201 — its position was revealed by the strange movements of a star being quickly flung around a massive, invisible counterpart. This sparkling group of stars also has some strange properties which make it unique amongst the over 150 globular clusters belonging to the Milky Way. NGC 3201 has an extremely fast velocity with respect to the Sun and its orbit is retrograde, meaning that it moves speedily in the opposite direction to the galactic centre, which it orbits.

Vending Telemeter  The unusual behavior of this cluster suggests that it may have extragalactic origins, but at some point was captured by the Milky Way’s gravity. However, the chemical makeup of this intriguing cluster tells a different story — the stars within NGC 3201 are chemically very similar to those of other galactic globular clusters, implying that they formed at a similar location and time to their neighbours.

Whether this mysterious cluster was adopted by our galaxy or has for some reason evolved very differently to the family of clusters it grew up with, it is certainly an unusual astronomical beauty.

Credit: Sarajedini et al.; ESA/Hubble & NASA

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[inhandnetworks-blog]

Terra Satellite Sees Shadows of Solar Eclipse in the Arctic Oc Industrial IoT Manufacturer  ean

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NASA’s Terra satellite captured this view of the clouds in th Remote access IoTe Arctic Ocean during last week’s total solar eclipse.

During the morning of m2m communication   March 20, 2015, a total solar eclipse was visible from parts of Europe, and a partial solar eclipse from northern Africa and northern Asia. NASA’s Terra satellite passed over the Arctic Ocean on March 20 at 10:45 UTC vending computer  (6:45 a.m. EDT) and captured the eclipse’s shadow over the clouds in the Arctic Ocean.

Image: NASA Goddard MODIS Rapid Response Team

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Physicists Generate Laser-Like Beams of X-Rays UMTS router   from a Tabletop Device

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CU-Boulder physics profess industrial equipmentors and JILA fellows Henry Kapteyn and Margaret Murnane stand next to one of their laser devices. Photo by Glenn Asakawa/University of Colorado

Physicists have generated the first laser-like beams of X-rays from a tabletop device, opening the door for devices that may be used by scientists to gain a better understanding of the nanoworld.

An international research team led by the University of Colorado Boulder has generated the first laser-like beams of X-rays from a tabletop device, paving the way for major advances in many fields including medicine, biology and nanotechnology development.

For half a century, scientists have been trying to figure out how to build a cost-effective and reasonably sized X-ray laser that could, among other things, provide super-high-resolution imaging, according to Henry Kapteyn, a CU-Boulder physics professor and fellow at JILA, a joint institute of CU-Boulder and the National Institute of Standards and Technology. Such a device also could be used by scientists to peer into a single cell or chemical reaction to gain a better understanding of the nanoworld.

Most of today’s X-ray lasers require so much power that they rely on facilities the size of football stadiums or larger, making their use impractical. To avoid the need for a large energy source to power an X-ray laser, the CU-Boulder researchers have created a tabletop device that uses atoms in a gas to efficiently combine more than 5,000 low-energy mid-infrared laser photons to generate each high-energy X-ray photon, said Margaret Murnane, a CU-Boulder physics professor and JILA fellow who is co-leading the research efforts.

“Because X-ray wavelengths are 1,000 times shorter than visible light and they penetrate materials, these coherent X-ray beams promise revolutionary new capabilities for understanding and controlling how the nanoworld works on its fundamental time and length scales,” Murnane said. “Understanding the nanoworld is needed to design and optimize next-generation electronics, data and energy storage devices and medical diagnostics.”

The findings will appear June 8 in the journal Science.

The tabletop device — an X-ray tube in the soft X-ray region — produces a bright, directed beam of X-rays by ensuring that all of the atoms in a multi-atmosphere pressure gas emit X-rays, according to Kapteyn.

“As an added advantage, the X-rays emerge as very short bursts of light that can capture the fastest processes in our physical world, including imaging the motions of electrons,” Kapteyn said.

Laser beams, which are visible light, represent one of the best ways to concentrate energy and have been a huge benefit to society by enabling the Internet, DVD players, laser surgery and a host of other uses.

“However, the same revolution that happened for visible light sources that made it possible to create laser-like beams of light for widespread use instead of multidirectional light from a light bulb, is only now happening for X-rays,” Kapteyn said.

Co-authors on the paper were Tenio Popmintchev, Ming-Changiot vending machine Chen, Dimitar Popmintchev, Paul Arpin, Susannah Brown, Andreas Becker and Agnieszka Jaron-Becker of CU-Boulder; Skirmantas Alisauskas, Giedrius Andriukaitis, Tadas Balciunas, Oliver Mucke, Audrius Pugzlys and Andrius Baltuska of the Vienna University of Technology in Vienna; industrial LTE router   Bonggu Shim, Samuel E. Schrauth and Alexander Gaeta of Cornell University; and Carlos Hernandez-Garcia and Luis Plaja of the Universidad de Salamanca in Salamanca, Spain.

Image: Glenn Asakawa/University of Colorado

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New Evidence That the Moon Formed Via Earth Co opencart webdesign  llision with Planet-Sized Body

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By using refined techniques to compare the measurements of oxygen isotopes in lunar samples with those from Earth, a team of astronomers has provided new evidence that the Moon formed from the collision of the  Cellular modem  Earth with another planet-sized astronomical body.

A new series of measurements of oxygen isotopes provides increasing evidence that the Moon formed from the collision of the Earth with another large, planet-sized astronomical body, around 4.5 billion years ago. This work is published in Science, and will be presented to the Goldschmidt geochemistry conference in California on 11th June.

Most planetary scientists believe that the Moon formed from an impact between the Earth and a planet-sized body, which has been given the name Theia. Efforts to confirm that the impact had taken place had centered on measuring the ratios between the isotopes of oxygen, titanium, silicon and ot m2m  hers. These ratios are known to vary throughout the solar system, but their close similarity between Earth and Moon conflicted with theoretical models of the collision that indicated that the Moon would form mostly from Theia, and thus would be expected to be compositionally different from the Earth.

Now a group of German researchers, led by Dr. Daniel Herwartz, have used more refined techniques to compare the ratios of 17O/16O in lunar samples, with those from Earth. The team initially used lunar samples which had arrived on Earth via meteorites, but as these samples had exchanged their isotopes with water from Earth, fresher samples were sought. These were provided by NASA from the Apollo 11, 12 and 16 missions; they were found to contain significantly higher leve WiFi M2M Router ls of 17O/16O than their Earthly counterparts.

Dr Herwartz said “The differences are small and difficult to detect, but they are there. This means two things; firstly we can now be reasonably sure that the Giant collision took place. Secondly, it gives us an idea of the geochemistry of Theia. Theia seems to have been similar to what we call E-type chondrites. If this is true, we can now predict the geochemical and isotopic composition of the Moon, because the present Moon is a mixture of Theia and the early Earth. The next goal is to find out how much material of Theia is in the Moon”.

Most models estimate that the Moon it is composed of around 70% to 90% material from Theia, with the remaining 10% to 30% coming from the early Earth. However, some models argue for as little as 8% Theia in the Moon. Dr Herwartz said that the new data indicate that a 50:50 mixture seems possible, but this needs to be confirmed.

The team used an advanced sample preparation technique before measuring the samples via stable isotope ratio mass spectrometry, which showed a 12 parts per million (± 3 ppm) difference in 17O/16O ratio between Earth and Moon.

Dr Daniel Herwartz will present “The elevated Δ17O composition of the Moon relative to the Earth” to the Goldschmidt conference, Sacramento, California, on 11th June at 09.45, Eastern Time. The Goldschmidt conference is the world’s leading annual conference on geochemistry, 2014/

Publication: Daniel Herwartz, et al., “Identification of the giant impactor Theia in lunar rocks,” Science 6 June 2014: Vol. 344 no. 6188 pp. 1146-1150; DOI:10.1126/science.1251117

Image: NASA

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Giant Oligocene Ka industrial l2tp cellular router  iruku Penguins Stood Nearly Five Feet Tall

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Paleontologists have reconstructed a model of the Kairuku penguin that stood almost 4 feet 6 inches in height in what’s now New Zealand. The Kairuku penguin lived approximately 25 million years ago, in the Oligocene epoch, i Vending Telemetry  n the Chattian age.

The Oligocene is often viewed by paleontologists as a time of transition, between the archaic world of the tropical Eocene and the modern Miocene. The major changes during the Oligocene included a global expansion of grasslands and the regression of tropical board leafed forests to the equatorial belt. The start of the Oligocene is marked by the Eocene-Oligoscene extinction event that is also known as the Grande Coupure, which was marked by large-scale extinction and floral and faunal turnover, from European to Asian. The Oligocene-Miocene boundary is not easily identified worldwide, but it can be seen in regional boundaries.

The Kairuku, a Maori word that stands for diver who returns with food, was reconstructed from fossilized bones that were collected in 1977 by Ewan Fordyce, a paleontologist from the University of Otago, in New Zealand.

Dan Ksepka, from North Carolina State University, wa Dual SIM M2M router s first interested by the bones because of the unusual shape of the body that they suggested. The Kairuku was an elegant bird, with a slender body, long flippers, and short, thick legs and feet. The unusual shape would have made the reconstruction stand six feet tall, if they would have used an extrapolation based upon the length of the flippers.

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The reconstruction was built using two separate fossils and the skeleton of an existing king penguin. The Kairuku would have been the largest of the five species that lived in New Zealand during the Oligocene. The results of the research were published in the Journal of Vertebrate Paleontology.

[via Wired UK]

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New Cell-Wei inhand networks  ghing Technique Could Help Doctors Choose Cancer Drugs

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Cells pass through an sSMR device, which consists of multiple sensors that are fluidically connected in series and separated by delay channels (not all is shown). This design enables a stream of cells to flow through the device such that different sensors can concurrently weigh flowing cells in the stream.

Doctors have many drugs available to treat multiple myeloma, a type of blood cancer. However, there is no way to predict, by genetic markers or other means, how a patient will respond to a particular drug. This can lead to months of treatment with a drug that isn’t working.

Researchers at MIT have now shown that they can use a new type of measurement to predict how drugs will affect cancer cells taken from multiple-myeloma patients. Furthermore, they showed that their predictions correlated with how those patients actually fared when treated with those drugs.

This type of testing could help doctors predict drug responses based on measurements of cancer cell growth rates after drug exposure, says Scott Manalis, the Andrew and Erna Viterbi Professor in the MIT departments of Biological Engineering and Mechanical Engineering and a member of MIT’s Koch Institute for Integrative Cancer Research.

“For infectious diseases, antibiotic susceptibility testing based on cell proliferation has been extremely effective for many decades,” Manalis says. “Unlike bacteria, analogous tests for tumor cells have been challenging, in part because the cells don’t always proliferate upon removal from the patient. The measurement we developed doesn’t require proliferation.”

Manalis is the senior author of the study, which appears in the Nov. 20 issue ofNature Communications. The paper’s lead authors are Mark Stevens, a visiting scientist at the Koch Institute and research scientist at Dana-Farber Cancer Institute, and Arif Cetin, a former MIT postdoc.

An animation of how a serial suspended micro channel resonator functions with car router   cells flowing through the device. Cells pass over 10 cantilever mass sensors to have their mass weighed over a 15 minute interval, with measurements spaced by delay channels. Multiple measurements allow the researchers to capture changes in mass over time, a metric called mass accumulation rate (MAR).

Predicting response

The researchers’ new strategy is based on technology that Manalis and others in his lab have developed over the past several years to weigh cells. Their device, known as a suspended microchannel resonator (SMR), can measure cell masses 10 to 100 times more accurately than any other technique, allowing the researchers to precisely calculate growth rates of single cells over short periods of time.

The latest version of the device, which can measure 50 to 100 cells Industrial 3G Router   per hour, consists of a series of SMR sensors that weigh cells as they flow through tiny channels. Over a 20-minute period, each cell is weighed 10 times, which is enough to get an accurate MAR measurement.

A few years ago, Manalis and colleagues set out to adapt this technique to predict how cancer drugs affect tumor cell growth. They showed last year that the mass accumulation rate (MAR), a measurement of the rate at which the cells gain mass, can reveal drug susceptibility. A decrease in MAR following drug treatment means the cells are sensitive to the drug, but if they are resistant, there is no change in MAR.

In the new study, the researchers teamed up with Nikhil Munshi at Dana-Farber Cancer Institute to test a variety of drugs on tumor cells from multiple-myeloma patients. They then compared the results to what happened when the patients were treated with those drugs. For each patient, they tracked the cells’ response to three different drugs, plus several combinations of those drugs. They found that in all nine cases, their data matched the outcomes seen in patients, as measured by clinical protein biomarkers found in the bloodstream, which are used by doctors to determine whether a drug is killing the tumor cells.

“When the clinical biomarkers showed that the patients should be sensitive to a drug, we also saw sensitivity by our measurement. Whereas in cases where the patients were resistant, we saw that in the clinical biomarkers as well as our measurement,” Stevens says.

Personalized medicine

One of the difficulties in treating multiple myeloma is choosing among the many drugs available. Patients usually respond well to the f wireless networking  irst round of treatment but eventually relapse, at which point doctors must choose another drug. However, there is no way to predict which drug would be best for that particular patient at that time.

In one scenario, the researchers envision that their sensor would be used at the time of disease relapse, when the tumor may have developed resistance to specific therapies.

“At this time of relapse, we would take a bone marrow biopsy from a patient, and we would test each therapy individually or in combinations that are typically used in the clinic. At that point we’d be able to inform the clinician as to which therapy or combinations of therapies this patient seems to be most sensitive or most resistant to,” Stevens says.

The new test holds “great promise” to screen myeloma cells for drug susceptibility, says Kenneth Anderson, a professor of medicine at Harvard Medical School and Dana-Farber Cancer Institute, who was not involved in the research.

“This assay may fast-forward personalized medical care and the choice of effective therapies for myeloma both at diagnosis and at relapse,” Anderson says.“It may also be useful to profile susceptibility of minimal residual disease in order to further inform therapy and improve patient outcome.”

Bone marrow biopsies often produce limited numbers of tumor cells to test — as few as 50,000 tumor cells in this study — but for this technique that is enough to test many different drugs and drug combinations. The MIT researchers have started a company to begin a larger clinical study for validating this approach, and they plan to investigate the possibility of using this technology for other types of cancer.

The research was funded by the National Institutes of Health, the Koch Institute’s Cancer Center Support (core) Grant from the National Cancer Institute, the Department of Veterans Affairs, a Koch Institute Quinquennial Cancer Research Fellowship, and the Bridge Project of the Koch Institute and Dana-Farber/Harvard Cancer Center.

Publication: Arif E. Cetin, et al., “Determining therapeutic susceptibility in multiple myeloma by single-cell mass accumulation,” Nature Communications 8, Article number: 1613 (2017) doi:10.1038/s41467-017-01593-2

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Nanocrystalline  LTE router  Alloys that Meet Operational Requirements

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A transition electron microscope image of the structure of the new tungsten-titanium alloy, after being exposed to a high temperature of 1,100 degrees Celsius for a week. The image shows that the alloy retains its nanocrystalline structure even after this heat treatment. Image courtesy of Chookajorn et al, from Science

In a newly published research paper, MIT scientists describe the method they used to identify and fabricate nanocrystalline alloys that meet operational requirements, even at elevated temperatures.

Most metals — from the steel used to build bridges and skyscrapers to the copper and gold used to form wires in microchips — are made of crystals: orderly arrays of molecules forming a perfectly repeating pattern. In many cases, including the examples above, the material is made of tiny crystals packed closely together, rather than one large crystal. Indeed, for many purposes, making the crystals as small as possible provides significant advantages in performance, but such materials are often unstable: The crystals tend to merge and grow larger if subjected to heat or stress.

Now, MIT researchers have found a way to avoid that problem. They’ve designed and made alloys that form extremely tiny grains — called nanocrystals — that are only a few billionths of a meter across. These alloys retain their nanocrystalline st Vending Telemeter  ructure even in the face of high heat. Such materials hold great promise for high-strength structural materials, among other potential uses.

The new findings, including both a theoretical basis for identifying specific alloys that can form nanocrystalline structures and details on the actual fabrication and testing of one such material, are described in a paper published Aug. 24 in Science.

Tongjai Chookajorn (in white blouse) and Heather Murdoch (in blue dress) are working with Christopher Schuh to discover new nanocrystalline alloys of metals that preserve their granular structure under intense thermal conditions…Photo by Dominick Reuter

Graduate student Tongjai Chookajorn, of MIT’s Department of Materials Science and Engineering (DMSE), guided the effort to design and synthesize a new class of tungsten alloys with stable nanocrystalline structures. Her fellow DMSE graduate student, Heather Murdoch, came up with the theoretical method for finding suitable combinations of metals and the proportions of each that would yield stable alloys. Chookajorn then successfully synthesized the material and demonstrated that it does, in fact, have the stability and properties that Murdoch’s theory predicted. They, along with their advisor Christopher Schuh, the Danae and Vasilis Salapatas Professor of Metallurgy and department head of DMSE, are co-authors of the paper.

For decades, researchers and the metals industry have tried to create alloys with ever-smaller crystalline grains, Schuh says. But, he adds, “nature does not like to do that. Nature tends to find low-energy states, and bigger crystals usually have lower energy.”

Looking for pairings with the potential to form stable nanocrystals, Murdoch studied many combinations of metals that are not found together naturally and have not been produced in the lab. “The conventional metallurgical approach to designing an alloy doesn’t think about grain boundaries,” Schuh explains, but rather  Industrial IoT Router/Gateway  focuses on whether the different metals can be made to mix together or not. But, he adds, it’s the grain boundaries that are crucial for creating stable nanocrystals. So Murdoch came up with a way of incorporating these grain boundary conditions into the team’s calculations.

Why go to the trouble of designing such materials? Because they can have properties that other, more conventional metals and alloys do not, the researchers say. For example, the alloy of tungsten and titanium that the MIT researchers developed and tested in this study is likely exceptionally strong, and could find applications in protection from impacts, guarding industrial or military machinery or for use in vehicular or personal armor. But the researchers stress that this fundamental research could lead to a wide range of potential uses. “This is one case study, but there are potentially hundreds of alloys we could make,” Schuh says.

Other nanocrystalline materials designed using these methods could have additional important qualities, such as exceptional resistance to corrosion, the team says. But finding materials that will remain stable with such tiny crystal grains, out of the nearly infinite number of possible combinations and proportions of the dozens of metallic elements, would be nearly impossible through trial and error. “We can calculate, for hundreds of alloys, which ones work, and which don’t,” Murdoch says.

The key to designing nanocrystalline alloys, they found, is “finding the systems where, when you add an alloying element, it goes to the grain boundaries and stabilizes them,” Schuh says, rather than distributing uniformly through the material. Under classical metallurgical theory, such a selective arrangement of materials is not expected to occur.

The tungsten-titanium material that Chookajorn synthesized, which has grains just 20 nanometers across, remained stable for a full week at a temperature of 1,100 degrees Celsius — a temperature consistent with proces M2M IoT router  sing techniques such as sintering, where powdered material is packed into a mold and heated to produce a solid shape. This means this alloy could easily become a practical material for a variety of applications where its high strength and impact resistance would be important, the researchers say.

Julia Weertman, a professor emerita of materials science and engineering at Northwestern University, says this work “represents a significant advancement toward the goal of creating nanocrystalline alloys that are usable at elevated temperatures.” She adds that “Schuh and his students, using thermodynamic considerations, derived a method to choose alloys that will remain stable at high temperatures. … This research opens up the use of microstructurally stable nanocrystalline alloys in high temperature applications, such as engines for aircraft or power generation.”

The work was funded by the U.S. Army Research Office.

Image: Chookajorn et al, from Science

Reprinted with permission of MIT News

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