"Ghost Heart" - The Art of Decellularization

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"Ghost Heart" - The Art of Decellularization
Decellularization eh?
Save your Spinach
Through a series of experiments, a team of researchers have grown beating human heart cells on spinach leaves!
āCurrent bioengineering techniques, like 3-D printing, canāt build the intricate, branching network of blood vessels that makes up the heart tissue. However, a team of researchers from the Worcester Polytechnic Instituteā¦
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#decellularization #cuoredecellularizzato #anatomiatiamo #heart #decellularizzazione ā£āš
Can you imagine what it will be like 50 years from now?
Can you imagine what it will be like 50 years fromĀ now?
Scientists have grown the entire forelimb of a rat in a lab . . . and it moves!
Ā Hidden in plain sight Godās miraculous secrets* Waiting to be found
Bernhard Jank, MD/Ott Laboratory, Massachusetts General Hospital Center for Regenerative Medicine
Dr. Harold Ott, head of theĀ Ott Laboratory for Organ Engineering and Regeneration,Ā and his team at Massachusetts General Hospital in BostonĀ were able toā¦
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A team of scientists at Massachusetts General Hospital in Boston made news earlier this month when they published research in the journal Biomaterials describing how they'd created the world's first bioartificial limb in the laboratory.
Or, in other words: scientists have now grown the entire forelimb of a rat in a lab.
Dr. Harold Ott, head of the Ott Laboratory for Organ Engineering and Regeneration,and his team were able to "engineer rat forelimbs with functioning vascular and muscle tissue," according to the hospital.
The scientists used a process called decellularization. They removed the living tissue from an existing rat limb, leaving just a "framework" ā made of things like proteins ā behind. Then they re-populated that "scaffolding" with new, living cells.
This may be an important first step leading to the eventual creation of functional, bioartificial limbs that could be used in transplants. That could be a step up from existing prosthetic devices.
In Massachusetts Lab, Scientists Grow An Artificial Rat Limb
Photo: Bernhard Jank, MD/Ott Laboratory, Massachusetts General Hospital Center for Regenerative Medicine
Decellularization is the name for a tissue engineering technique which is designed to strip the cells from a donor organ, thus leaving nothing but connective tissue that once held the cells in place. Itās referred to as aĀ āghost organāĀ for itās pale appearance. It can then be reseeded with the patientās cells. The goal is to render an organ that can be transplanted into a patient without the tissue being rejected.
A decellularised organ is one that has been submerged in a solution that kills all living cells, leaving only theĀ proteinĀ matrixĀ behind. The decellularised "ghost heart" can then be placed in living bodies to help understand broken tissue and organ rejections of that living flesh.