Like, normally I don’t particularly care, I had no issue with a female doctor or a female Bosley. I wouldn’t even be that fussed by any of the other characters being gender swapped, and they’ve done the same thing for Dr Cruces which seems interesting. I just feel like part of the Vetinari character is that, on the surface, he looks like your typical rich, white male character and that’s part of his power. He is aware of that and uses it. I mean his official title is the ‘Tyrant’ of Ank Morpork. Other rich, white, male characters come along expecting him to have the same prejudices only for him to turn around and completely obliterate them.
Plus I’m a little worried about how it might affect his/her interactions with other characters. There are characters that are fundamentally sexist. Less so in the night watch, but definitely with the wizards who barely admit that women exist. It is something that Pratchett challenges within the narrative but it does exist. I dunno, I just don’t know if a female Vetinari, particularly one apparently combining the characteristics of “Dracula and Elvis”.