The first Program Manager to present, Phillip Alvelda, opened the event with his mind blowing project to develop a working “cortical modem”. What is a cortical modem you ask? Quite simply it is a direct neural interface that will allow for the visual display of information without the use of glasses or goggles. I was largely at this event to learn about this project and I wasn’t disappointed. Leveraging the work of Karl Deisseroth in the area of optogenetics, the cortical modem project aims to build a low cost neural interface based display device. The short term goal of the project is the development of a device about the size of two stacked nickels with a cost of goods on the order of $10 which would enable a simple visual display via a direct interface to the visual cortex with the visual fidelity of something like an early LED digital clock. The implications of this project are astounding. Consider a more advanced version of the device capable of high fidelity visual display. First, this technology could be used to restore sensory function to individuals who simply can’t be treated with current approaches. Second, the device could replace all virtual reality and augmented reality displays. Bypassing the visual sensory system entirely, a cortical modem can directly display into the visual cortex enabling a sort of virtual overlay on the real world. Moreover, the optogenetics approach allows both reading and writing of information. So we can imagine at least a device in which virtual objects appear well integrated into our perceived world. Beyond this, a working cortical modem would enable electronic telepathy and telekinesis. The cortical modem is a real world version of the science fiction neural interfaces envisioned by writers such as William Gibson and more recently Ramez Naam. To the extent that it is real, the cortical modem is still a crude device. This isn’t going to give you a high fidelity augmented reality display soon. And since the current approach is based in optogenetics, it requires a genetic alteration of the DNA in your neurons. The health implications are unknown, and this research is currently limited to work with animal models. Specifically discussed was a real time imaging of the zebrafish brain with about 85,000 neurons.