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My boyfriend made this for me after a project I was doing went wrong
Oligonucleotides Manufacturing | Asymchem
Asymchem specializes in the high-quality manufacturing of oligonucleotides. Discover our advanced solutions for oligonucleotide synthesis and pharmaceutical applications.
Discover Asymchem, a top CDMO serving global pharma companies with innovative green solutions, advanced drug development, and manufacturing
Details Presentation Exactmer Ltd
Exactmer manufactures exact polymeric pharmaceuticals, enabling advanced therapies to be provided to all patients in need.Exactmer attains ISO9001 certification and launches development projects with new clients.Exactmer performs the first technology transfer of its Nanostar Synthesiser to a large pharmaceutical company.
Londoneast-uk Business and Technical Park,Yew Tree Avenue,Dagenham,RM10 7FN
+44 (0) 203 773 2216
https://exactmer.com/
How are 5-ROX and 6-ROX dyes different from one another?
How are 5-ROX and 6-ROX dyes different from one another? The ROX dye is connected to the nucleic acid molecule at spots 5 and 6, which are shown by the “5” and “6” prefixes. The dyes’ chemical characteristics and practical uses are similar; however, the dyes may have different fluorescence qualities. 5-ROX: This dye, which is usually attached to the 5′ end of an oligonucleotide probe, gives off…
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Antisense Oligonucleotide Market report features an extensive study of the current landscape and the likely future potential of single-use systems...
Presently, several drug developers, along with ASO technology providers, are actively engaged in the development of various antisense therapy candidates. Innovation in this field of research is mostly focused on improving cell targeting ability, target affinity, nuclease resistance, and optimizing toxicity profiles of antisense oligonucleotide candidates. Several big pharma players have also demonstrated interest in antisense oligonucleotide therapeutics and are investing both time and capital in this domain. The market has witnessed substantial partnership activity over the last few years. The activity in this segment of the industry has also attracted the attention of both private and public sector investors / investment funds, which have extended financial support to the initiatives of capable developer companies.
The oligonucleotide synthesis, modification and purification services market is anticipated to grow at a CAGR of 18%, till 2030, claims Roots Analysis
Over the past few years, oligonucleotide developers have outsourced complex manufacturing procedures to specialty contract manufacturing service providers, in order to address growing demand competitively, economically and profitably
Roots Analysis has announced the addition of “Oligonucleotide Synthesis, Modification and Purification Services Market: Focus on Research, Diagnostic and Therapeutic Applications, 2021-2030” report to its list of offerings.
Since the approval of the first antisense drug in 1998, oligonucleotides have paved their way into the therapeutic segment, owing to their ability to treat a myriad of disease indications and high target specificity. This presents lucrative opportunities for contract service providers that offer manufacturing services for this rapidly evolving class of pharmacological intervention. As a consequence, oligonucleotide manufacturers are increasingly strengthening their capabilities and capacities, in order to cater to the growing demand.
To order this 360+ page report, which features 175+ figures and 225 + tables, please visit https://www.rootsanalysis.com/reports/view_document/oligonucleotide-synthesis/304.html
Key Market Insights
Over 95 companies claim to offer oligonucleotide manufacturing services
The market landscape is currently dominated by the presence of small firms (1-50 employees), which represents close to 41% of the total number of industry stakeholders. This is followed by mid-sized players (~30%), and large and more established firms (~29%). Further, close to 14% of the service providers claim to offer manufacturing services for research diagnostic and therapeutic applications.
Partnership activity has increased at a CAGR of over 47% within this domain, since 2014
Majority of the agreements (34%) were inked to offer manufacturing services to oligonucleotide-based product developers, followed by instances of mergers / acquisitions (26%), aimed at the consolidation of existing service portfolios.
Multiple expansion initiatives were undertaken by service providers, between 2015 and 2021
Over 49% of such initiatives were focused on establishment of new facilities, followed by expansion of manufacturing-related capabilities (26%). Further, the US emerged as the most active country (in terms of number of expansion initiatives), followed by China and Germany.
440+ oligonucleotides focused clinical trials have been registered, worldwide
The clinical research activity (in terms of number of trials registered) increased at a CAGR of 41%, during the period 2013-2020. Of the total number of trials, close to 67% have already been completed, while 31% studies are presently active.
North America has emerged as oligonucleotide manufacturing hub, in terms of installed capacity
At present, the annual, installed manufacturing capacity in US and EU is estimated to capture around 80% of the available global capacity. This is primarily driven by players having commercial scale expertise / capabilities.
Demand for oligonucleotides is anticipated to grow at a CAGR of 10.5%, during 2021-2031
Given the fact that several oligonucleotide-based drug products were approved in the last 3-4 years, the commercial demand for oligonucleotides is anticipated to increase in the near future. Interestingly, over 76% of the estimated commercial demand was observed to have generated from antisense oligonucleotides.
Antisense Oligonucleotides and siRNAs are anticipated to capture over 86% of the market share in 2030
At present, the aforementioned types of oligonucleotides capture close to 79% of the total revenues. It is worth mentioning that the contract manufacturing market for oligonucleotides in Asia-Pacific is anticipated to grow at a relatively faster pace (20%).
To request a sample copy / brochure of this report, please visit this link
Key Questions Answered
§ Who are the leading players offering oligonucleotide synthesis, modification and purification services for research, diagnostic and therapeutic applications?
§ What are the preferred modification and purification methods used for oligonucleotides?
§ What are the key challenges faced by stakeholders engaged in this domain?
§ What kind of partnership models are commonly adopted by industry stakeholders?
§ What are the recent expansion initiatives undertaken by service providers within this domain?
§ Which therapy developers are likely to partner with oligonucleotide manufacturing service providers?
§ What is the annual, clinical and commercial demand for oligonucleotides?
§ What is the current, installed manufacturing capacity for oligonucleotides?
§ What percentage of oligonucleotide manufacturing operations are outsourced to service providers?
§ What factors should be taken into consideration while deciding whether the manufacturing operations for oligonucleotides should be kept in-house or outsourced?
§ What are the different initiatives undertaken by big pharma players engaged in this domain, in the recent past?
§ What are the opportunities in emerging markets for oligonucleotide manufacturing?
§ How is the current and future market opportunity likely to be distributed across key market segments?
§ What are the anticipated future trends related to oligonucleotide manufacturing?
The financial opportunity within the oligonucleotide synthesis, modification and purification market has been analyzed across the following segments:
§ Application Area
Research and Diagnostic Applications
Therapeutic Applications
§ Type of Oligonucleotide
Antisense Oligonucleotides
miRNA
shRNA
siRNA
Others
§ Scale of Operation
Clinical
Commercial
§ Purpose of Production
In-house Operations
Outsourced Operations
§ Type of Operation
API
FDF
§ Size of Manufacturer
Small
Mid-sized
Large
§ Key Therapeutic Areas
Autoimmune Disorders
Cardiovascular Disorders
Genetic Disorders
Infectious Diseases
Metabolic Disorders
Neuromuscular Disorders
Oncological Disorders
Ophthalmic Disorders
Other Therapeutic Areas
§ Key Geographical Regions
North America
Europe
Asia-Pacific and the Rest of the World
The report features inputs from eminent industry stakeholders, according to whom, the oligonucleotide manufacturing services market is primarily driven by the increasing demand for such molecules, for use in diagnostic and therapeutic applications. The report includes detailed transcripts of discussions held with the following experts:
§ Arun Shastry (Co-Founder and Managing Director, Hanugen Therapeutics)
§ Hans-Peter Vornlocher (Managing Director, Axolabs)
§ Joachim Bertram (Chief Scientific Officer and Managing Director, IBA Life Sciences)
§ Tobias Pohlmann (Founder and Managing Director, BianoScience)
The research covers detailed profiles; each profile features a brief company overview, its financial information (if available), along with information on its service portfolio, manufacturing facilities, details on partnerships, recent developments (expansions), and awards received by the firm, as well as an informed future outlook.
§ Agilent Technologies
§ Ajinomoto Bio-Pharma Services
§ BioSpring
§ CordenPharma
§ Integrated DNA Technologies
§ Kaneka Eurogentec
§ LGC Biosearch Technologies
§ Lonza
§ Microsynth
§ Nitto Denko Avecia
§ Sigma Aldrich
§ STA Pharmaceutical
§ Sumitomo Chemical
§ Thermo Fisher Scientific
§ TriLink Biotechnologies
For additional details, please visit
https://www.rootsanalysis.com/reports/view_document/oligonucleotide-synthesis/304.html or email [email protected]
You may also be interested in the following titles:
1. Pharmaceutical Contract Manufacturing Market (3rd Edition), 2021-2030
2. Biopharmaceutical Contract Manufacturing Market (4th Edition), 2021-2030
3. Antisense Oligonucleotide Therapeutics Market, 2020-2030
4. RNAi Therapeutics Market (2nd Edition), 2019 - 2030
Contact:
Ben Johnson
+1 (415) 800 3415
+44 (122) 391 1091
The oligonucleotide synthesis, modification and purification services market
Over the past few years, oligonucleotide developers have outsourced complex manufacturing procedures to specialty contract manufacturing service providers, in order to address growing demand competitively, economically and profitably
Roots Analysis has announced the addition of “Oligonucleotide Synthesis, Modification and Purification Services Market: Focus on Research, Diagnostic and Therapeutic Applications, 2021-2030” report to its list of offerings.
Since the approval of the first antisense drug in 1998, oligonucleotides have paved their way into the therapeutic segment, owing to their ability to treat a myriad of disease indications and high target specificity. This presents lucrative opportunities for contract service providers that offer manufacturing services for this rapidly evolving class of pharmacological intervention. As a consequence, oligonucleotide manufacturers are increasingly strengthening their capabilities and capacities, in order to cater to the growing demand.
To order this 360+ page report, which features 175+ figures and 225 + tables, please visit https://www.rootsanalysis.com/reports/view_document/oligonucleotide-synthesis/304.html
Key Market Insights
Over 95 companies claim to offer oligonucleotide manufacturing services
The market landscape is currently dominated by the presence of small firms (1-50 employees), which represents close to 41% of the total number of industry stakeholders. This is followed by mid-sized players (~30%), and large and more established firms (~29%). Further, close to 14% of the service providers claim to offer manufacturing services for research diagnostic and therapeutic applications.
Partnership activity has increased at a CAGR of over 47% within this domain, since 2014
Majority of the agreements (34%) were inked to offer manufacturing services to oligonucleotide-based product developers, followed by instances of mergers / acquisitions (26%), aimed at the consolidation of existing service portfolios.
Multiple expansion initiatives were undertaken by service providers, between 2015 and 2021
Over 49% of such initiatives were focused on establishment of new facilities, followed by expansion of manufacturing-related capabilities (26%). Further, the US emerged as the most active country (in terms of number of expansion initiatives), followed by China and Germany.
440+ oligonucleotides focused clinical trials have been registered, worldwide
The clinical research activity (in terms of number of trials registered) increased at a CAGR of 41%, during the period 2013-2020. Of the total number of trials, close to 67% have already been completed, while 31% studies are presently active.
North America has emerged as oligonucleotide manufacturing hub, in terms of installed capacity
At present, the annual, installed manufacturing capacity in US and EU is estimated to capture around 80% of the available global capacity. This is primarily driven by players having commercial scale expertise / capabilities.
Demand for oligonucleotides is anticipated to grow at a CAGR of 10.5%, during 2021-2031
Given the fact that several oligonucleotide-based drug products were approved in the last 3-4 years, the commercial demand for oligonucleotides is anticipated to increase in the near future. Interestingly, over 76% of the estimated commercial demand was observed to have generated from antisense oligonucleotides.
Antisense Oligonucleotides and siRNAs are anticipated to capture over 86% of the market share in 2030
At present, the aforementioned types of oligonucleotides capture close to 79% of the total revenues. It is worth mentioning that the contract manufacturing market for oligonucleotides in Asia-Pacific is anticipated to grow at a relatively faster pace (20%).
To request a sample copy / brochure of this report, please visit this link
Key Questions Answered
§ Who are the leading players offering oligonucleotide synthesis, modification and purification services for research, diagnostic and therapeutic applications?
§ What are the preferred modification and purification methods used for oligonucleotides?
§ What are the key challenges faced by stakeholders engaged in this domain?
§ What kind of partnership models are commonly adopted by industry stakeholders?
§ What are the recent expansion initiatives undertaken by service providers within this domain?
§ Which therapy developers are likely to partner with oligonucleotide manufacturing service providers?
§ What is the annual, clinical and commercial demand for oligonucleotides?
§ What is the current, installed manufacturing capacity for oligonucleotides?
§ What percentage of oligonucleotide manufacturing operations are outsourced to service providers?
§ What factors should be taken into consideration while deciding whether the manufacturing operations for oligonucleotides should be kept in-house or outsourced?
§ What are the different initiatives undertaken by big pharma players engaged in this domain, in the recent past?
§ What are the opportunities in emerging markets for oligonucleotide manufacturing?
§ How is the current and future market opportunity likely to be distributed across key market segments?
§ What are the anticipated future trends related to oligonucleotide manufacturing?
The financial opportunity within the oligonucleotide synthesis, modification and purification market has been analyzed across the following segments:
§ Application Area
Research and Diagnostic Applications
Therapeutic Applications
§ Type of Oligonucleotide
Antisense Oligonucleotides
miRNA
shRNA
siRNA
Others
§ Scale of Operation
Clinical
Commercial
§ Purpose of Production
In-house Operations
Outsourced Operations
§ Type of Operation
API
FDF
§ Size of Manufacturer
Small
Mid-sized
Large
§ Key Therapeutic Areas
Autoimmune Disorders
Cardiovascular Disorders
Genetic Disorders
Infectious Diseases
Metabolic Disorders
Neuromuscular Disorders
Oncological Disorders
Ophthalmic Disorders
Other Therapeutic Areas
§ Key Geographical Regions
North America
Europe
Asia-Pacific and the Rest of the World
The report features inputs from eminent industry stakeholders, according to whom, the oligonucleotide manufacturing services market is primarily driven by the increasing demand for such molecules, for use in diagnostic and therapeutic applications. The report includes detailed transcripts of discussions held with the following experts:
§ Arun Shastry (Co-Founder and Managing Director, Hanugen Therapeutics)
§ Hans-Peter Vornlocher (Managing Director, Axolabs)
§ Joachim Bertram (Chief Scientific Officer and Managing Director, IBA Life Sciences)
§ Tobias Pohlmann (Founder and Managing Director, BianoScience)
The research covers detailed profiles; each profile features a brief company overview, its financial information (if available), along with information on its service portfolio, manufacturing facilities, details on partnerships, recent developments (expansions), and awards received by the firm, as well as an informed future outlook.
§ Agilent Technologies
§ Ajinomoto Bio-Pharma Services
§ BioSpring
§ CordenPharma
§ Integrated DNA Technologies
§ Kaneka Eurogentec
§ LGC Biosearch Technologies
§ Lonza
§ Microsynth
§ Nitto Denko Avecia
§ Sigma Aldrich
§ STA Pharmaceutical
§ Sumitomo Chemical
§ Thermo Fisher Scientific
§ TriLink Biotechnologies
For additional details, please visit
https://www.rootsanalysis.com/reports/view_document/oligonucleotide-synthesis/304.html or email [email protected]
You may also be interested in the following titles:
1. Pharmaceutical Contract Manufacturing Market (3rd Edition), 2021-2030
2. Biopharmaceutical Contract Manufacturing Market (4th Edition), 2021-2030
3. Antisense Oligonucleotide Therapeutics Market, 2020-2030
4. RNAi Therapeutics Market (2nd Edition), 2019 - 2030
Contact:
Ben Johnson
+1 (415) 800 3415
+44 (122) 391 1091
As per the reports released by the team of Market Research Future (MRFR), the global Oligonucleotide Synthesis Market is expected to grow significantly in the coming years. The market is …
Oligonucleotide Synthesis Market : In-Depth Research Report 2019 – 2027