For those who use CCleaner as their junk file remover, there's a little extra you can always add, if you're up to it.
http://singularlabs.com/software/ccenhancer/
Singularlabs developed a neat little add-on, which is just an .ini file that provides more options, in cleaning junk and garbage files.
Extremely handy for those who really with to conserve as much space as possible on their OS partition.
I've just discovered this neat little utility last month and have been using it on all three of my systems (2 laptops; 1 desktop).
You can download the .ini file from the official website to update CCleaner manually on computers that don't have internet access.
Otherwise, the general installer program can update to the latest .ini file with customized options* for cleaning.
*All customized options for cleaning can be noted an asterisk.
Really great for finding install locations and other areas of interest for cleaning.
Caution: Used at your own discretion. Check the locations you really want to clean, if you know what you are doing and that the programs of interest involved are, indeed, working correctly.