Wegovy and Ozempic are not just in the drugstore: alpha cells are allies and make them on their own
Alpha cells represent ~30–40% of the endocrine cells in the human islet and are the “emergency brake” against hypoglycemia: when blood glucose levels drop, they release glucagon, which stimulates hepatic glucose production. Glucagon release is driven by metabolic signals (ionic channels) paracrine inputs (insulin and somatostatin inhibit it; mediators released by alpha- and beta-cells can…

















