#human genome sequencing

[nuadox]

Complete human genome finally sequenced

- By Nuadox Crew -

After more than twenty years of research, scientists have finally provided the first complete, gapless human genome sequence.

When scientists announced the complete sequence of the human genome in 2003, they were fudging a bit.

In fact, nearly 20 years later, about 8% of the genome has never been fully sequenced, largely because it consists of highly repetitive chunks of DNA that are hard to align with the rest.

But a three-year-old consortium has finally filled in that remaining DNA, providing the first complete, gapless genome sequence for scientists and physicians to refer to.

The newly completed genome, dubbed T2T-CHM13, represents a major upgrade from the current reference genome, called GRCh38, which is used by doctors when searching for mutations linked to disease, as well as by scientists looking at the evolution of human genetic variation.

Among other things, the new DNA sequences reveal never-before-seen detail about the region around the centromere, which is where chromosomes are grabbed and pulled apart when cells divide, ensuring that each “daughter” cell inherits the correct number of chromosomes. Variability within this region may also provide new evidence of how our human ancestors evolved in Africa.

Source: Robert Sanders; University of California, Berkeley

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[jeff-rose]

Researchers Extract Complete Human Genome From Ancient ‘Chewing Gum’ via /r/CurrentGeek http://bit.ly/2EyaIIO

[jueekate-blog]

On-going research activities along with supportive regulations across the globe will revolutionize digital genome market. The growing implementation of this technology in the field of personalized …

Get more details @ http://bit.ly/2nUpHlT

Some of the key companies providing products and services in the digital genome market are Thermo Fisher, Perkin Elmer, Qiagen, Illumina, Becton Dickinson. Agilent, Sigma Aldrich, Fluidigm, Pacific Biosciences, F. Hoffmann-La Roche, Agios, AVEO Oncology and Biomarin, BioReference.

[qkgroups-blog]

Illumina may sequence a genome for $100

Illumina may sequence a genome for $100

DNA sequencing company Illumina has unveiled a machine that may one day sequence a whole genome for less than $100. The company’s CEO Frank deSouza showed the machine, NovaSeq, at the JP Morgan Healthcare Conference in downtown San Francisco. He said that the machine could decipher an entire human genome in less than an hour.

Cost of sequencing has gone down tremendously. In 2006 Illumina’s first…

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[rferl]

New Genome Decoder Holds Promise, Raises Ethics Questions

What can you learn about a person in a day? You can note their eye color and height, find out whether they have siblings, and perhaps what they like to do in their free time. But how about learning that a person is genetically predisposed to developing colon cancer, or is likely to never go bald? [READ MORE]