SUMMARY: Y/n is a human born from a werewolf family. She was diagnosed with a rare disease and thought that there were no cure to it. But they managed to find it towards the end, though.
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It was very unlikely for a werewolf to have a disease considering their ability to recover faster than humans and their ability to fight any illness. However, that doesn’t happen to Y/n.
When she was a baby, Y/n was diagnosed with a rare disease, a cause for her blood mutation since she was born from a couple of werewolf parents. It’s a rare disease and Y/n was the fifth omega child in the werewolves community across the world to be diagnosed with it. And since it’s rare, not even the doctor knew the cure. They didn’t even have a name so they just call it “The Rare Disease” and the symptoms are always the same.
She gets feverish almost every month ever since she was baby. Despite being an omega who came from a strong werewolf family line (hell, her little sister is an alpha), she cannot protect herself in many situation. Her brain will get fuzzy if she stays under the hot sun too long. She cannot get too cold either. Her dietry is also weird (which contains a massive amount of meat that not even her sister needed it).
All in all, Y/n had a very tough life growing up especially when she won’t be able to change into her wolf form because of her disease. She will only be able to have their senses.
Y/n’s little sister sticks with her through every episode of her sickness. The toughest one was when she got into heat for the first time, but it gets tougher over the next few of her heats and by the time Y/n was old enough to actually take a knot like other omegas do when they’re in heat, Y/n was not able to do it. Every time an alpha knots her, her body temperature will rise. Her body will be very hot and soon, she pass out. That happens many times that none of the alphas would want to knot her second time.
But that’s until the Winchester brothers came into their lives.
* * *
When Y/n and her sister first met the Winchester brothers, they were sitting at the park bench and were reading a witchcraft book. Y/n saw the disgusted look on their Dean’s face when he saw what they were reading and immediately, Y/n knew that Dean hates witches. They introduce themselves, exchanging smiles and looks and handshakes. In Dean’s part, he felt something when his skin touches with Y/n, but Y/n doesn’t look like she notices it.
Dean had wondered if Y/n was really good at masking it. He had never thought Y/n was human because she doesn’t really smell like one.
Ever since then, Y/n tried to be as close to Dean whenever she can but she was very careful not get suspicious because Dean’s smell calm her nerves. She didn’t tell him. She didn’t tell her sister. She’s not ready for her sister to know it yet especially when she knows with the sickness, she won’t live so much far long.
But knowing what her heat could do to Dean, she'd secluded herself from the other two alphas. Her sister will bring her somewhere else they know Y/n will be safe and will stay with her until she’s calm (though that means she passed out a couple of times during her heat). Meanwhile, Dean at the bunker was agitated.
After a few months of letting Y/n and her sister to live with them at the bunker (plus, they’re very good teammates when hunting), Dean knows and is very sure of it that Y/n is his mate. He knows Y/n is his mate. He knows when Y/n’s in heat because he could feel it in their bond and he’s a mess. He started to throw things inside his bedroom every time he could feel the mild pain his mate was feeling.
Dean didn’t understand why Y/n had to drive away whenever she’s in heat when her mate is right in front of her. Though Dean never confessed, nor did they talk about it, but Dean knew y/n knows. But why? If she knows Dean’s her mate, why is she running away while dean could help her during her heat?
That happens for a very long time until Y/n finally decided to slowly adapted her current situation. Y/n decided to stay at the bunker when she’s in heat, but asked her little sister for Dean’s shirt to accompany her in her room. Y/n’s sister was quite surprised to hear that, but she didn’t ask any more questions because she understood. And she had to sneak into Dean’s room to get his shirt.
But Sam caught Y/n's sister in the middle of stealing and not a second after that, Dean appeared.
“Shit.” Y/n’s sister mutters.
"What're you doing?" He asked the same question Sam asked.
Y/n's sister tried to lie for Y/n, but then decided to be honest since she's already caught red-handed. Y/n's sister told the brothers the truth (that Y/n's mate is Dean and the reason why Y/n never wanted dean nor Sam to know is because she's sick and dying and she doesn't want Dean to suffer her lost).
“You’re an alpha,” Dean said. “You know how it feels like for not being able to handle your omega mate.”
“She’s not a werewolf, Dean. She’s human, but she has an omega traits. That’s why it’s called Rare Disease.”
“But still--”
“And I don’t have an omega or a mate yet, but--”
“No, but you’re an alpha. Do you see how protective you are with your sister? Imagine that, but 10 times more protective towards your mate.”
Y/n's sister asked Dean to give her some more time, or at least until Y/n's heat over to discuss about it. Dean agreed and allowed Y/n's sister to grab a few more of his shirts for Y/n. Dean even allows Y/n’s sister to grab his pillows to Y/n to get comfortable in bed.
Y/n still doesn't want Dean to help her with her heat. Because of her illness, her heat always came strong. She tried with other alphas before and they knotted them a couple of times a night, but none of them managed to soothe Y/n's heat. They left Y/n alone to handle her own heat because they cannot help her. So just like every other alpha, Y/n doesn't think dean could help.
But Y/n's sister told Y/n to try. At least slowly. Let Dean be by her side at first. And when Y/n agreed and Dean was with her during her heat, Dean couldn't help much and he was devastated for not being able to help Y/n especially when she was writhing in pain. Dean was quite astounded to have witness Y/n's heat because he'd never seen heat so bad before. But Dean decided to search on the cure, hope there were cures. Sam and Y/n's sister helped too.
But they couldn't find any cure even when they reach the point when Y/n allowed Dean to knot her. Now most of other omega's heat are slowly faded when their alphas knotted them, but not y/n. Her bad heat still continues and Dean was messed up. Dean has to admit that he was exhausted helping Y/n.
Y/n became more sick. She felt unwanted. She felt as if Dean doesn't want her anymore. She felt like killing herself. Y/n and Dean had rough months especially when Y/n started to yell at Dean from time to time. When Dean got his rut and Y/n cannot help, she felt so useless. Dean felt their bond loosened, but still he didn't leave her. He felt bitter with their relationship sometimes, yes, but he never once thought of leaving her.
Dean was more messed up when Y/n suddenly fell onto unconsciousness this one day and Dean remembers that it's supposed to be her heat. Y/n was still breathing though she was in a slumber. And Dean, Sam and Y/n's sister fought hard to find Y/n's cure until one day, Y/n's sister mind was suddenly brought back when Y/n was born. She was visited by a black figure and it was sucking her blood.
Dean hates vampires. So so so bad but he bad no choice to meet them more specifically at their nest. He had to beg for one of the vampire's blood (more to the leader's strong blood) to feed Y/n. They made a deal that Sam and Dean are not to hunt vampires anymore. Once again, reluctantly Dean had to agree.
Once home, Dean quickly went to his room where Y/n was still sleeping on his bed. He made Y/n drink the blood until it's finished and hoped for Y/n to wake up but Y/n didn't wake up soon. She only wakes up three days after that.
Y/n was a little pale when she meets her sister, Sam and her mate at the reading table. “Dean?" Her heart was shaking and it's not only her heart that she could hear, but the others too. Not that she couldn't hear them before, but more intense now like she could hear blood streaming in their veins, or the soft notes of their breathings. And she could see more prominent too. Like Dean's green eyes under the yellow reading light even from afar.
“Y/n? You're awake?”
Dean chased after Y/n and there's a small part of her that wants to run to be naughty around with Dean, but decided not to and let Dean hugs her tightly there. “How're you feeling?”
“Um, good.” She smiled at Dean. “And, um, healthy.” She chuckled softly and nervously. “I don't know how more to describe just...I just like I'm ready for everything.”
“You sure?” Dean's eyebrow raised and there was a naughty smirk at the end of his lips.
“Guys! Come on!” Y/n's sister raised her voice, acknowledging the couple that she and Sam exist in the room with them. “Y/n just wake up and you decided to go lovey-dovey instantly? Don't I get a hug from my sister? Man, I'm so worried about you! We've been trying to find a cure but couldn't find any until I got a flashback from when you were little--”
“Ah, right, right, that dream.”
“You knew?!” Almost everyone in the room looked at her in surprised.
“No, I don't until I passed out. I dreamed of mom and I guess she helped me send that memory to you.”
“Oh, sweetheart.” Dean hugged Y/n again. One arm linked around her shoulder meanwhile the other behind her head when he feels her shaking. “That's okay. You're safe now. And we're fine now.”
Y/n linked her arms around Dean's torso and inhaled his scent. The scent that can make her go crazy.