SARS-CoV-2 Omicron JN.1 subvariants KP.3.1.1 and XEC emerged as dominant over parental strains. Wang et al. show that KP.3.1.1 and XEC are s
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Highlights • KP.3.1.1 and XEC are 1.3- to 1.6-fold more resistant to serum neutralization than KP.3 • KP.2 MV booster may elicit higher titers against KP.3.1.1 and XEC than JN.1 infection • Spike mutations F59S and S31Δ are functionally similar for receptor binding and mAb evasion













