another thing that comes to my mind a lot is Van Kleiss. I've already mentioned before that he represents trans-humanism, or perhaps more accurately post-humanism. but the way that the writers and animators get the idea across is so interesting.
his very existence seems to cause the world to go mad.
I made this AMV a couple years ago about good ol' VK, and a lot of it's scenes demonstrate what I'm talking about:
but especially the scene where he's fighting White Knight and turns a nearby tree into an EVO.
Van Kleiss represents a new age, one in which the human race as we know it has no place or role. the changes he brings about reflect this alien new world.
my comparison is not without basis. the comic series Generator Rex was based off of was called Machinima Rex (or M Rex for short), which was about the world evolving around mankind to the point where it no longer dominant.
honestly the best comparison I can give for his coming is the arrival of an Outer God, specifically Nyarlethotep. I know this sounds like a stretch, but hear me out:
There was a daemoniac alteration in the sequence of the seasons—the autumn heat lingered fearsomely, and everyone felt that the world and perhaps the universe had passed from the control of known gods or forces to that of gods or forces which were unknown. [...] Into the lands of civilisation came Nyarlathotep, swarthy, slender, and sinister, always buying strange instruments of glass and metal and combining them into instruments yet stranger. He spoke much of the sciences—of electricity and psychology—and gave exhibitions of power which sent his spectators away speechless, yet which swelled his fame to exceeding magnitude. Men advised one another to see Nyarlathotep, and shuddered. And where Nyarlathotep went, rest vanished; for the small hours were rent with the screams of nightmare.
-HP Lovecraft's poem, Nyarlethotep
Yet Van Kleiss is a man. A man who, through technology, cruelty, and force of will, made himself immortal, unkillable, master of nature, space, and time, even if only for a brief moment were all those aspects united.
this is post-humanism. this is the promise of a world without man; a world populating by things that used to be human but are more, or perhaps less, than human.
"Are you a man, or a god?"
"I find both labels rather... limiting. [...] You may call me Van Kleiss."