Maxillofacial Trauma Important Notes 1. Classification Of Fracture Classification Of Fractures Of Maxilla: Lefort classification Lefort 1 L
Maxillofacial Trauma

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Maxillofacial Trauma Important Notes 1. Classification Of Fracture Classification Of Fractures Of Maxilla: Lefort classification Lefort 1 L
Maxillofacial Trauma
💌 BMC Journal of Translational Medicine⠀ ✍🏻 Synergic effects of decellularized bone matrix, hydroxyapatite, and extracellular vesicles on repairing of the rabbit mandibular bone defect model 📄 Background: Extracellular vesicles (ECV) and bone extracellular matrix (ECM) have beneficial effects on the treatment of some pathological conditions. The purpose of this study was to find the synergic effects of decellularized bone (DB) ECM and ECVs on the repair of rabbit. 📄 Methods: The quality of decellularized sheep bones was confirmed by H&E, Hoechst, DNA quantification, immunohistochemistry, histochemical staining, and scanning electron microscopy (SEM). Osteoblast-derived ECVs were evaluated by internalization test, Transmission electron microscopy, Dynamic light scattering, and flow cytometry for CD9, CD63, CD81 markers. The hydrogel containing DB and hydroxyapatite (HA) with or without ECVs was evaluated for osteoblast functions and bone repair both in vitro and in vivo. 📚 Results: The data indicated ECM preservation after decellularization as well as cell depletion. In vitro assessments revealed that mineralization and alkaline phosphatase activity did not improve after treatment of MG63 cells by ECVs, while in vivo morphomatrical estimations showed synergic effects of ECVs and DB + HA hydrogels on increasing the number of bone-specific cells and vessel and bone area compared to the control, DB + HA and ECV-treated groups. 📋 Conclusion: The DB enriched with ECVs can be an ideal scaffold for bone tissue engineering and may provide a suitable niche for bone cell migration and differentiation. 📄 Keywords: ⠀ Decellularized bone, Extracellular vesicle, Hydroxyapatite, Tissue engineering⠀ #Maxillofacialsurgery #Oralandmaxillofacialsurgery #Maxillofacialtrauma #surgery #surgeon #article #omfs #drtavanafar #drsaeidtavanafar #جراحی_فک #جراحی_زیبایی #جراحی_بینی #جراحی_دهان #دکترتوانافر #دکترسعیدتوانافر https://www.instagram.com/p/CKv28i-Huzs/?igshid=19ptb8ji0vl8e
❗Warning❗ This post contains graphical and Surgical content. Viewer discretion is advised ❗هشدار❗ این پست حاوی تصاویر جراحی است. 🔶 Case: Squamous Cell Carcinoma of Left Side of Maxilla, Extending to Left Orbital Floor. - Patient had received three session of chemotherapy before surgery which has reduced the tumor size significantly. - Patient is currently tumor free. Many thanks goes to @dr_daneste_hossein #oralsurgery #Maxillofacialsurgery #Oralandmaxillofacialsurgery #Maxillofacialtrauma #scc#squamouscellcarcinoma#residency#omfsresident#maxillofacialpathology #Carcinoma #drtavanafar #drsaeidtavanafar #جراحی_صورت#جراحی_بینی #جراحی_فک #جراحی_فک_صورت #جراحی_دهان_فک_و_صورت #دکترتوانافر #دکترسعیدتوانافر (at Rajaei Trauma Hospital بیمارستان ترومای رجایی) https://www.instagram.com/p/CDgMBuEg3Jl/?igshid=1izrr3ssvwoza