#medications notes

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Rates of Absorption by Administration

-- sublingual = rapid

-- per rectum = rapid

-- by mouth = slow

-- intravenous = immediate

-- intraosseous = immediate

-- inhalation = rapid

-- intranasal = rapid

-- intramuscular = moderate

-- subcutaneous = slow

-- transcutaneous = slow

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[er-cryptid]

Hematology Drugs

anticoagulant drugs -- prevent blood clots from forming -- heparin inhibits clotting factors -- warfarin inhibits vitamin K

corticosteroid drugs -- anti-inflammatory drugs -- suppress immune response -- decrease inflammation -- given to organ transplant recipients to prevent organ rejection

erythropoietin -- stimulates red marrow to make erythrocytes

immuno-suppressant drugs -- suppress the immune response -- prevent rejection of a transplanted organ

nucleoside reverse transcriptase inhibitors -- antiretroviral drugs -- inhibit reverse transcriptase -- HIV requires this enzyme to reproduce

platelet aggregation inhibitor drugs -- prevent platelets from clumping together -- this clumping is the first step in forming a blood clot

protease inhibitor drugs -- antiretroviral drugs -- inhibit protease -- HIV requires this enzyme to reproduce

thrombolytic enzyme drugs -- break fibrin strands -- dissolves a blood clot that has already formed

tissue plasminogen activator drugs -- TPA drugs -- activate plasminogen -- convert plasminogen to an enzyme that breaks fibrin strands -- dissolves a blood clot that has already formed

vitamin B12 drugs -- used to treat pernicious anemia -- routes      -- nasal spray      -- intramuscular injection

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[er-cryptid]

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Megestrol

Names -- Megace

Class -- antineoplastic -- hormone (progestin)

Use -- pallative treatment of endometrial / breast carcinoma -- may be combined with surgery or radiation tablets -- treatment of anorexia, weight loss, and cachexia from AIDS

Action -- antineoplastic effect may result from inhibition of pituitary function -- progestins increase appetite in AIDS-related anorexia

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