Itsumi Toudou has had such a wild growth as a character (and the protagonist of Sorry, I'm not into Yuri). At the start of the story she's a bit odd and sad.
The girl who starts the story with what is later established in this art style to mean the signs she's been crying a lot. And it turns out a lot means crying herself to sleep every night.
Until she got the power to affect change in her life. And did that change go well for her?
No. Things do not get better.
But she does feel more in control of her life. That if she just schemes some more, if she just uses her new found empathy to guess how other people are feeling and do what they want, she'll finally be loved and appreciated.
And it does pan out, by chapter 53 (current chapter as of writing), she has become the emotional support for a few dozen girls in her school and one outside, and a grown lady who until now was a living weapon and now has greater access to her own emotions and wants (she also at one point made a bunch of grudges and evil spirits catch feelings for her, but it's a manga so that's just par for the course). She also has two girlfriends, and a dozen or so girls who want to bone her cause she's just that cool.
Things are looking up for Itsumi Toudou, but she did have to fight for it. The moral of this manga: never kill yourself, something incredibly gay and emotionally satisfying might happen.