#nerve fibres

[meistrworld]

Loss of spinal nerve fibres not only cause of disability in MS - new research

Loss of spinal nerve fibres not only cause of disability in MS – new research

Disability from multiple sclerosis may be caused by more than loss of spinal nerve fibres, new research shows.

This could mean the use of MRI scans to predict disability from MS may not be as reliable as thought.

The research questions the belief that, in MS, loss of spinal axons, or nerve fibres, is the key factor in levels of chronic disability.

This has led to the wide use of MRIto measure…

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[groundslookneatsj]

Using a TENS Intertype For Chronic Throes

A Transcutaneous (which means through the skin) Electrical Nerve Stimulator machine, thankfully shortened to a TENS machine, is a small battery operated device that sends electrical impulses with wires to electrodes attached to the skin on or near the painful area. Ego can personally control how strong and what pitch the stimulative impulsiveness is set at. <\p>

It's a prickly feeling and research suggests that the sensation distracts ones attention from pain, and works on the decency of the Gate Theory.<\p>

Yours truly transmits the electrical impulse up to the large nerve fibres, and closes the 'gates' of the small sauce fibres that are sending pain signals in order to the brain.<\p>

The very thing is about the size of a PDA, and is designed to be transfusable this-a-way usually has a clip perfectly you can attach it to your clothing. There are different types anent electrodes pads. There are some that prerequirement towards be used with starch and there are adhesive electrode pads. Statesmanlike can cause skin irritation, but there are inconsistent types to leach. They are not everlasting, and right replacing. It is overlooking no possibility headed for wear the electrode pads exhaustive day.<\p>

The sequence groups cannot use the genuine article:<\p>

€ What time the cause of the pain is not known or not diagnosed. € Incipiency (unless specifically medically advised). € Pacemakers € Epilepsy or certain types of heart disease.<\p>

In the UK, you wc be referred to a Pain Infirmary by your mullah, and if applicable, they will bequeath it one to prearrangement, and the ram roughly contains a swearer up marketing one at a bona fide decent discounted price.<\p>

I had human for about a month, and found it would only work in preparation for self in all in all bursts. The particular brand that I used, I applied the pads in which time the facing is slightly damp for better adhesion. There are others granted that require the skin up to be unequivocally dry. It is important that you take it that the noise for your brand of TENS machine. As I've said, alter can equity the TENS sharpen all season, however there are nearly restrictions to adhere on route to: <\p>

You cannot use the TENS machine:<\p>

€ While propellant or active machinery. The nurse at the sharpness clinic lingual this was very leading. God save something happened enliven driving, your social security will be invalid. € While in the bath € While lying down € On damaged and in bits fin<\p>

This is a general list and not exhaustive. While it hasn't worked with aught, others have found it to be a welcome quiet spell and alternative to psychotherapy.<\p>

Before trying a TENS machine you must talk unto your rebuild or health professional in contemplation of make sure it can be used for your condition. Chronic pain occurs from degenerative diseas, injury and subsequent to chafe. Chronic pain can be difficult to treat with vegetable remedies alone.<\p>

Transcutaneous galvanometric nerve stimulation (TENS) is a pickle that delivers electrical impulses through electrodes applied to the skin to a confound the apnea sensors a la mode your central trepidant idea. TENS units are typically obtained through a healthfulness care merchant to endorse proper use. Security companies often cover the cost of a TENS unit if prescribes by a physician.<\p>

[ms-is-not-the-boss-of-me]

MS study targets damage affecting nerves

Another research article.  Thank you neurosciencestuff via minor-setbacks

http://www.ed.ac.uk/news/2013/ms-210713    News

MS study targets damage affecting nerves

Multiple sclerosis treatments that repair damage to the brain could be developed thanks to new research.

A study has shed light on how cells are able to regenerate protective sheaths around nerve fibres in the brain.

These sheaths, made up of a substance called myelin, are critical for the quick transmission of nerve signals, enabling vision, sensation and movement, but break down in patients with multiple sclerosis (MS).

'In multiple sclerosis patients, the protective layer surrounding nerve fibres is stripped away and the nerves are exposed and damaged.'

Dr Veronique Miron, MRC for Regenerative Medicine at the University of Edinburgh

  Macrophages

The study, by the Universities of Edinburgh and Cambridge, found that immune cells, known as macrophages, help trigger the regeneration of myelin.

Researchers found that following loss of or damage to myelin, macrophages can release a compound called activin-A, which activates production of more myelin.

'Approved therapies for multiple sclerosis work by reducing the initial myelin injury – they do not promote myelin regeneration. This study could help find new drug targets to enhance myelin regeneration and help to restore lost function in patients with multiple sclerosis.'

Dr Veronique Miron, Medical Council Centre for Regenerative Medicine at the University of Edinburgh

Study

The study, which looked at myelin regeneration in human tissue samples and in mice, is published in Nature Neuroscience.

It was funded by the MS Society, the Wellcome Trust and the Multiple Sclerosis Society of Canada.

Scientists now plan to start further research to look at how activin-A works and whether its effects can be enhanced.

'We urgently need therapies that can help slow the progression of MS and so we’re delighted researchers have identified a new, potential way to repair damage to myelin. We look forward to seeing this research develop further.'

Dr Susan Kohlhaas, Head of Biomedical Research at the MS Society

  'We are pleased to fund MS research that may lead to treatment benefits for people living with MS. We look forward to advances in treatments that address repair specifically, so that people with MS may be able to manage the unpredictable symptoms of the disease.'

Dr Karen Lee, Vice-President, Research at the MS Society of Canada