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Ofatumumab (Mechanism of Action)
Ofatumumab (Mechanism of Action)
In this article, we will discuss Ofatumumab (Mechanism of Action). So, let’s get started. Mechanism of ActionOfatumumab binds specifically to both the small and large extracellular loops of the CD20 molecule. The CD20 molecule is expressed on normal B lymphocytes (pre–B- to mature B-lymphocyte) and on B-cell CLL. The CD20 molecule is not shed from the cell surface and is not internalized…
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Ofatumumab
In this article, we will discuss Ofatumumab (Dosage Overview). So, let’s get started. IndicationsPreviously Untreated Chronic Lymphocytic LeukemiaOfatumumab is indicated, in combination with chlorambucil, for the treatment of previouslyuntreated patients with chronic lymphocytic leukemia (CLL) for whom fludarabine-based therapy is considered inappropriate.Extended Treatment in CLLOfatumumab is…
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Un traitement prometteur pour les symptômes de la sclérose en plaques S'il n'existe pas encore de traitement curatif de la sclérose en plaques, diverses équipes de recherche visent à en atténuer les symptômes.
Nuevo estudio con ofatumumab sobre celulas B en la EM.
Nuevo estudio con ofatumumab sobre celulas B en la EM.
Un nuevo estudio sugiere que atacar a las células B, que son un tipo de glóbulos blancos en el sistema inmune, puede estar asociado con la reducción de la actividad de la enfermedad para las personas con esclerosis múltiple (EM). El estudio se ha publicado hoy, y será presentado en la Academia Americana en la 66a Reunión Anual de la Neurología en Filadelfia, abril 26-mayo 3, 2014. (more…)
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