#oocyte

[bpod-bpod]

Long Life Eggs

Oocytes [egg cells] – with a female mammal from birth – provide cytoplasm for a resulting embryo so must be maintained in good condition over a long time. This study shows how potentially damaging protein aggregates are stored for degradation in 'compartments' (vesicle assemblies) in the oocyte

Read the published research article here

Still from a video from work by Gabriele Zaffagnini and colleagues

Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain

Video originally published with a Creative Commons Attribution 4.0 International (CC BY-NC 4.0)

Published in Cell, February 2024

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[microscope-world]

Oocyte In Vitro Fertilization, image captured using the ZEISS IVF inverted microscope.

[cellimagelibrary]

Image of the Week - September 2, 2019

CIL:39469 - http://www.cellimagelibrary.org/images/39469

Description: Fluorescent micrograph of stage V-VI Xenopus laevis oocytes surrounded by thousands of follicle cells, as visualized by Hoechst staining.

Authors: Vincent Pasque

Licensing: Attribution-NonCommercial-NoDerivs 2.0 UK: England & Wales (CC BY-NC-ND 2.0 UK)

[anatomic-study]

… 原始卵胞は分裂・増殖することができる⠀ ○ ×⠀ ⠀ (解答) ×⠀ まず、卵母細胞と卵胞の区別をしっかりしておいてください。卵母細胞がすなわち卵子です。卵母細胞が卵胞上皮細胞に包まれたものが卵胞です。⠀ 卵母細胞の起源は卵祖先細胞で、胎生期にさかんに分裂増殖しますが、出生前に卵祖細胞の分裂は止まり、一次減数分裂前期の状態で停止します。この状態の細胞を卵母細胞とよび、これ以降は増殖することはありません。この卵母細胞が一層の卵胞上皮細胞で包まれたものが原始卵胞で出生時にはおおよそ700万個あると言われます。⠀ ⠀ #解剖学 #生殖器系 #女性生殖器 #卵祖細胞 #oogonia #卵母細胞 #oocyte #卵胞 #ovarian_follicle ⠀ ⠀ 【一問一答】⠀ http://bit.ly/qanda62

[lilacwintersky]

// new phone who dis???

Mun got herself a new phone today so happy munday ~

[bpod-bpod]

Baby Gap

Life is full of give and take – cells and tissues exchange chemicals with each other, often pushing them through tiny channels in cell membranes. There is another way though, making use of the gaps where cells meet in the epithelium – the skin-like barrier that coats many of our tissues – but what controls this paracellular transport is a little mysterious. Here a mesh of epithelial cells (purple) nestles a developing egg cell in a fruit fly ovary. Pictured under a confocal fluorescence microscope, the cells form triangular junctions that expand or contract to create temporary intercellular spaces (green), long enough for yolk-forming proteins to squeeze through to the egg. With a similar mechanism helping chemicals move from the blood into mammalian testes, future work may unravel the role of paracellular transport in human fertility and development too.

Written by John Ankers

Image from work by Jone Isasti-Sanchez and colleagues

Institute of Animal Physiology, University of Münster, Münster, Germany

Image copyright held by the original authors

Research published in Developmental Cell, April 2021

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[cellimagelibrary]

Image of the Week - April 22, 2019

CIL:39036 - http://cellimagelibrary.org/images/39036

Description: A photomicrograph of a stained semi-thin section of mouse ovary, showing a maturing Graafian follicle. The ovary contains many follicles that contain immature oocytes (egg cells). The follicle is important to support maturation and also develops through a number of stages as the ooctye matures. This process of folliculogenesis includes; the immature dormant primordial follicle, primary follicle, secondary follicle and tertiary stage follicle before ovulation occurs. The tertiary stage follicle is also called an antral or Graafian follicle characterised by a large fluid filled space (or antrum). The Graafian follicle also contains a fully mature oocyte at its full size complete with zona pellucida.

Author: Spike Walker

Licensing: Attribution-NonCommercial-NoDerivs 2.0 UK: England & Wales (CC BY-NC-ND 2.0 UK)

[bpod-bpod]

No Default Sex

Male and female embryos start out roughly the same, but as development progresses, the tissues that will ultimately become sperm- or egg-producing structures are either retained or eliminated, depending on sex. It was thought that genes present only on the Y chromosome controlled the development of male-specific structures, and that the lack of a Y chromosome resulted in female-specific structures. In other words, that male development was an active process and female development the default. It is now clear, however, that the development of female sex organs is active too. Researchers have discovered a factor produced in female mice necessary for the elimination of male-specific tissues. The mutant embryo (bottom) lacks this factor and thus retains both female and male precursor tissues (pink and blue). This new discovery should help to inform studies into both intersex development and certain reproductive problems.

Written by Ruth Williams

Image from work by Fei Zhao and colleagues

Reproductive Developmental Biology Group, National Institute of Environmental Health Sciences, Durham, NC, USA

Image copyright held by the original authors

Research published in Science, August 2017

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