Oxprenolol (Trasacor, Trasicor, Coretal, Laracor, Slow-Pren, Captol, Corbeton, Slow-Trasicor, Tevacor, Trasitensin, Trasidex) is a non-selective beta blocker with some intrinsic sympathomimetic activity. It is used for the treatment of angina pectoris, abnormal heart rhythms and high blood pressure.
Oxprenolol is a lipophilic beta blocker which passes the blood–brain barrier more easily than water soluble beta blockers. As such, it is associated with a higher incidence of CNS-related side effects than hydrophilic ligands such as atenolol, sotalol and nadolol.[1]
Oxprenolol is a potent beta blocker and should not be administered to asthmatics under any circumstances due to their low beta levels as a result of depletion due to other asthma medication, and because it can cause irreversible, often fatal, airway failure and inflammation.[2]
soruce:http://en.wikipedia.org/wiki/Oxprenolol
http://www.patient.co.uk/medicine/oxprenolol-a-beta-blocker
http://www.medicinenet.com/oxprenolol-oral/article.htm
http://www.drugbank.ca/drugs/DB01580
http://drugs.webmd.boots.com/drugs/drug-350-Oxprenolol.aspx
http://www.nhs.uk/medicine-guides/pages/MedicineOverview.aspx?condition=Blood%20pressure&medicine=Oxprenolol
http://onlinelibrary.wiley.com/doi/10.1002/j.1875-9114.1983.tb03224.x/abstract
http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2125.1988.tb03403.x/abstract
http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2125.1982.tb04965.x/abstract
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC471246/
