#petct

[teachingrounds]

High expression of PSMA in prostate cancer makes it an attractive target for imaging and therapy. The left image shows a Prostascint scan (indium-111-capromab, an anti-PSMA antibody) in a patient with metastatic prostate cancer (black arrow). The FDA recently approved 2 PET radiopharmaceuticals that bind the extracellular domain of PSMA (Ga-68-gozetotide and F-18-piflufolostat). The right image shows an F-18-piflufolostat scan. The superior signal-to-noise and resolution of PET allow for detection of the tiny metastatic nodes seen in the pelvis.

Image credit

Left: Bhargava et al. Am. Jour. Nucl. Med. Mol. Imag. 2012.

Right: Dr. Thomas Anderson

[teachingrounds]

Clinical trials are also underway for PSMA-targeted therapy with alpha-emitting radionuclides. Alpha particles are much more energetic and thus cause more localized damage than beta particles. They do not travel as far in tissue, so they tend to have less toxicity. Image shows a patient with metastatic prostate cancer who had excellent response after 2 cycles of actinium-225-PSMA targeted alpha therapy (TAT). Reference: Zacherl et al. J. Nucl. Med. 2021, 62, 669-674.

#TeachingRounds#FOAMed#FOAMRad#Radiology#NuclearMedicine#PETCT

#Theransotics#NucMed#PSMA#radioligandtherapy#urology#oncology#alphatherapy

[teachingrounds]

PSMA PET can also help DOWNSTAGE some patients. This is an example of a patient who had an enlarged retroperitoneal lymph node (red arrow). Based on CT alone, this is highly suspicious for metastasis, however, on the PET scan this is not PSMA-positive and as such is not a metastasis (note the primary tumor is PSMA-positive - blue arrow). The patient was thus staged as N0M0. Image credit: Novartis.

[teachingrounds]

Our final PET tracers of the week are amyloid and tau PET tracers.

The FDA has approved 3 PET tracers for amyloid imaging: 18F-Florbetaben, 18F-Florbetapir, and 18F-Flutemetamol. Amyloid PET has greatest use in ruling out Alzheimer's dementia (AD; excellent NPV but poor PPV). The first image depicts a negative and positive amyloid PET. The key feature is loss of gray white differentiation in the positive scan. Image credit: UCSF Radiology.

One tracer is FDA-approved for detection of tau protein in neurofibrillary tangles in AD. This tracer is more specific and the amount of binding at PET correlates with severity of disease (2nd image). Reference: Fleisher et al. JAMA Neurology 2020.

[teachingrounds]

Today's radiology resource is The Xray Doctor, Dr. Vikash Shah. You can follow him on Facebook or Instagram, @thexraydoctor or on Twitter @DrVikasShah. Dr. Shah regularly posts excellent radiology cases - definitely worth following! This is a case of FDG avid axillary adenopathy with FDG activity in the ipsilateral deltoid muscle from COVID-19 vaccination. As more people get vaccinated, consider recent vaccination as a cause of axillary adenopathy on physical exam or any imaging study, especially if unilateral. Read the full case here:  https://www.instagram.com/p/CMCn-dKB2La/...

[bpknews]

గుంటూరు ప్రభుత్వ సర్వజన ఆసుపత్రిలో PET-CT స్కానింగ్ సేవలు ప్రారంభమయ్యాయి. రూ.20 వేల వరకు ఖర్చయ్యే స్కాన్లు ఇప్పుడు ఉచితంగా అందుబాటులోకి రావడం ప్రజలకు పెద్ద ఊరటగా మారింది.

రూ.20 వేల PET-CT స్కాన్ ఇప్పుడు ఉచితం | గుంటూరు GGHలో కొత్త సేవలు

గుంటూరు GGHలో రూ.18 కోట్లతో ఏర్పాటు చేసిన PET-CT యంత్రంతో పేదలకు ఉచిత క్యాన్సర్ స్కానింగ్ సేవలు అందుబాటులోకి వచ్చాయి.

GGH #PETCT #bpknews #bpknewsofficial #cleanvsgreensolutions #cgsolutions #pavanlawchambers #prasadamladdu #manabhimavarammanapavananna #pavanarmy59 #bjppavankumarb

[phantomhealthcare]

🏥✨𝐋𝐨𝐨𝐤𝐢𝐧𝐠 𝐭𝐨 𝐁𝐮𝐲 𝐨𝐫 𝐒𝐞𝐥𝐥 𝐈𝐦𝐚𝐠𝐢𝐧𝐠 𝐄𝐪𝐮𝐢𝐩𝐦𝐞𝐧𝐭? We’ve got you covered!

🌍 Trusted Global Network | Best Market Value We help hospitals, diagnostic centers & dealers worldwide trade imaging equipment smoothly and hassle-free.

🔹 𝐖𝐞 𝐃𝐞𝐚𝐥 𝐈𝐧: ✅ MRI Machines ✅ CT Scan Systems ✅ Cath Lab Equipment ✅ PET-CT Systems ✅ iDXA Lunar Machines ✅ Gamma Cameras

⚡ Fast Deals 🤝 Hassle-Free Process 🎯 Expert Support

🌐 www.phantomhealthcare.com

📩 Let’s discuss your requirements today! 📞 [phone] | [phone]

[hospitalinuppal]

PET CT Scan Types and Therapies – Discover Here

PET-CT scans merge PET and CT imaging to reveal metabolic and structural details, revolutionizing cancer diagnostics. Key types include FDG for broad oncology staging, PSMA for prostate cancer detection, DOTA for neuroendocrine tumors, FAPI for fibrotic cancers, and specialized scans like amyloid for Alzheimer's or cardiac viability. These enable theranostics like Lu-177 PSMA and DOTATATE therapies, pairing imaging with targeted radiation for precise treatment. At Kkswara Healthcare in Uppal, advanced facilities deliver these services locally.

PET-CT scans merge PET and CT to show body function and anatomy, helping detect, stage, and plan treatment for cancer.