Predictions for the Powerpuff Girls live-action series (based on what I know of the CW shows):
1) The Powerpuff hotline is now a smartphone app
2) Buttercup coming-out-of-the-closet character arc
3) Blossom-Brick angsty romance (superhero falling for a supervillain type of angst)
4) At least one villain will get killed by the Powerpuff Girls, as an attempt to make the PPG morally-grey.
5) Most of the fights will be in a warehouse
6) The Mayor will be written in a more villainous manner with him trying to start an affair with Miss Bellum, despite being married
7) At least one of the Powerpuff Girls will have daddy issues. Something that Professor Utonium did in the past caused the rift.
8) Samurai Jack appears in one episode as a way of setting up his series (it’ll be the Flash to the PPG’s Arrow). Also, let me just say this...if there’s ANY Cartoon Network series that deserves a dark live-action adaptation, it’s Samurai Jack. That’s literally just season 5.
9) At least one male character will be genderbent. If I had to pick, it’ll most likely be HIM (so...it’ll be HER in the live-action version).