#propofol

[innerward]

[neon-kazoo]

A Familiar Face

[Warnings: medical setting, coming out of sedation, IV mention]

Hero blinked, face contorting in a mix of confusion and discontent. Slowly, their surroundings came into view. A curtain, a small room cornered off by it, a figure by their feet. They laid on a bed lined with blue sheets with several white blankets layered over them. A nurse tapped quietly on a standing keyboard to their side.

They closed their eyes for another second, and when they opened them again the figure at their feet now loomed closer. It took a second, but Hero recognized the features peering down at them.

“Villain?!” They tried to exclaim, but it came out more as a cough. Their throat was dry and partially numb, making it difficult to form any subsequent words.

“What-“ they coughed again, falling into a short fit. The nurse laid a gentle hand on their arm, assuring them that that response was normal.

Momentarily distracted from their enemy’s presence in the room, Hero noticed their right arm feeling oddly cold. When they managed to untangle the limb from the sheets, an IV was revealed settled into the crook of their elbow.

Not that surprising, considering that it was there before they were put to sleep.

Hero gathered themselves, eventually able to ask weakly, “What are you doing here?”

“You asked me to drive you,” the villain replied, something disturbingly close to concern lurking behind their eyes as they gazed down at the formerly-sedated hero.

Hero narrowed their eyes suspiciously. They remembered signing in for the procedure, but they decidedly did not remember asking their nemesis to accompany them to the hospital.

“Yes, really. I can show you the paperwork if you want.”

Hero glanced to the nurse for help, but she too betrayed them with a confirmation.

Talk about being vulnerable, it didn’t get more trusting than asking your arch enemy to stay in the building while an anesthesiologist rendered you unconscious.

Hero didn’t have the energy to be concerned though, so they accepted the help of the rival that was shifting on their feet.

A change of clothes and a wheelchair ride later, Hero was settled into the front of the villain’s car, fully awake and ready to complain.

“I’m so hungry. Let’s stop at McDonald’s. I would die for some salty fries.”

“Sorry, you can’t eat yet,” Villain informed them apologetically.

Hero glanced at the clock and groaned.

“Some water, at least?” Hero begged.

“No on that too, I’m afraid.”

“What? So you just want me to starve?”

“Not me,” Villain replied easily, not bothering to take their eyes off the road to witness Hero’s grumbling, “Doctor’s orders.”

“So you let doctors do your dirty work now,” Hero huffed, crossing their arms over their chest.

They pointedly ignored the smile that spread across the criminal’s lips at their tantrum.

A long winded rant about dehydration followed.

When they were finally handed a water bottle an hour later, Villain had to snatch it right back out of their hands before they chugged it.

Don’t even get them started on the food an hour after that.

[petitegoose]

[tranquilsanatorium]

Anesthesia preparation

[k-star-holic]

Prosecution, "Oral administration of drugs" Yoo Ah-in Arrest warrant Rechengqu, Shanwei

Source: k-star-holic.blogspot.com

[mewmew-thehammer]

Anesthesia Doesn't Simply Turn Off the Brain – It Dramatically Changes and Controls Its Rhythms

Anesthesia Doesn't Simply Turn Off the Brain – It Dramatically Changes and Controls Its Rhythms

Simultaneous measurement of neural rhythms and spikes across five brain areas reveals how propofol induces unconsciousness. In a uniquely de

[veterinaryshitposting]

[scriptmedic]

Amanda on Patreon asked: 

I'm currently writing a story where my main character is infected with a secret weaponized virus he caught in a lab. It's got a lot of the qualities of meningitis with the added effect that he is hallucinating and terrified (he thinks those who want to help him are out to kill him).

The virus is progressing and they've finally caught him after a long chase, and brought him in for the miracle treatment that will hopefully work (you know that trope). But he's terrified and desperate, even as he gets sicker.

I'm planning to have him in wrist and ankle restraints, but I think it would be cruel to leave him without some pharmacological assistance to calm him down. They can't knock him out completely because they want to monitor the progress of the virus, but is there anything they can safely give him to keep him subdued? Still able to have a conversation, and it's fine if he's a little loopy (it'd be a great spot for a confession between him and another character) but I don't want him any more terrified than he already is. I read your posts on ketamine but I thought the hallucinogenic properties would only make things worse. 

Would midazolam be safe? Or haldol? Or is it unrealistic to sedate him at all? He will eventually lose consciousness on his own as the virus progresses, but I want him to be awake awhile first. 

(Forgot to mention, was considering a spinal tap since it's similar to meningitis with brain swelling, he'd have to be knocked out for that to stay still... how would they do that? Propofol?)

Hey there! Thanks so much for supporting the blog! 

Yes, midazolam would likely be a go-to choice. In fact, if there’s significant violence involved, a “5-and-2″ of 5mg of Haldol and 2mg of Ativan would be a very common dosage (and a favorite of one of one of my favorite hospitals). It’ll actually help the character, since it will keep him from harming himself, staff, and expending too much energy while he’s sick. 

Procedural sedation could theoretically be done with propofol, but someone is going to have to put in an IV. No bueno. (Many ERs don’t use propofol at all, actually; under their logic, this is an anesthesiology-only medication. I find this policy a bit odd and possibly unnecessary assuming quality ER staff, and I carry it on my ambulance, but...) 

In the ICU, the cuffs come off, and propofol is an excellent medication for sedation in this setting (once the IV is in). The reason is that it’s easy-on, easy-off; you can stop the infusion, assess someone neurologically, and put them right back under. Neuro ICUs love propofol. You can’t “shut off” a dose of Versed/midazolam and have it just stop working, it hangs around. Propofol makes it much easier to assess a patient. 

Propofol would definitely get this character deep enough to do a spinal tap :) 

Hope all this helps and thanks again! 

xoxo, Aunt Scripty

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