Cobel and Mark
Ok I have an idea for why Cobel seems to care about Mark now
I'm wondering if the original idea she had around Severance that got her to come up with it was as a way to help people with depression. Maybe she thought of it as a way people who are depressed could turn there brain off for a short amount of time and as a form of therapy have a different side of them selves find away to be happy in the world. It could have been the idea that things would cross over so the persons Innie would feed positive emotions into the Outie and help them with there depression.
If this is the case afterwards her original ideas clearly fell off the development at some point probably because of the Lumon board. Then Mark came along though a man who represented what she had been originally trying to do so she started doing experiments with him and Gemma to see if she could get the chips to do what she originally wanted to do. So my idea is that she cares about Mark because he's the kind of person she was originally trying to help when she came up with Severance.