I suppose the most important, burning animation question is this:
How progressively fucked up are they going to make Sprinkle look as time goes by in the show. Because let's be real, that poor weasel was kept alive by the power of Artagan and plot armor because he was just a pet and didn't go into combat (where he could then get hurt/ die fair and square like Trinket). So he was always "hiding in Jester's armor" lol.
Now here's the dilemma I think they're going to run across. The "Sprinkle longing for death" gag is one of the funniest things ever, but it is highly dependent on Travis and the rest giving voice to Sprinkle's woes as meta commentary. Without that, in a visual medium, unless they strike the balance just right, I think visual animal abuse just isn't that funny. In fact, I think done poorly it could very quickly turn the audience against Jester. Objectively, if you look at the situation stripped of comedy, Jester is a neglectful, abusive pet owner and should feel bad. But obviously that's missing some of the context of the show. And I think that somewhat intangible context is going to be difficult to translate to a visual medium. They could maybe play into the "are we SURE Sprinkle isn't undead? Gag with Fjord asking Caduceus to just double check or something. They could try to translate some bits of the meta into the character's mouths.
I think there's a good chance they'll skip it altogether and just have her be competent at pet care which is really too bad considering a good chunk of the audience already infantilizes Jester and ignores all of her flaws. Keeping one of the funny yet terrible things she did as a running gag would be good. And it's just so funny. Poor Sprinkle.