I don't even know how to feel about this. I obviously have been playing for too long.
Loki has a weird crush on Tony, and he's jealous of Sam when they spend time together, but he also doesn't? He's such an asshole, and he doesn't really show any affection, to anyone, actually. He's so caught up on his own schemes and manipulating people that anything with Tony would get caught up in that.
Tony is somehow always ok with people putting him down, and thats gonna have negative repercussions eventually (although the game is light-hearted and will probably never show it). He's also looking for a date, desperately enough that he's asking almost everyone, although he hasn't shown any explicit interest in Loki yet.
Tony's attention/approval seeking and Loki's manipulations are a bad mix, and any relationship that happens is going to be unhealthy, and especially painful for Tony.