An international team of researchers including scientists from The Australian National University (ANU) have developed a way to reveal the s
An international team of researchers including scientists from The Australian National University (ANU) have developed a way to reveal the smallest of malfunctions in the biochemical machinery that makes proteins in our bodies. According to the researchers, these malfunctions, however small, can trigger neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, as well as cancer and developmental disorders. The technique, which works by squeezing molecules through tiny holes in a silicon-based membrane, helps scientists understand how a mutation in a transfer RNA (tRNA) molecule—tRNA is a molecular messenger essential for building proteins—affects the molecule's real-time structure. The study is published in the journal Nucleic Acids Research.
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