A University of Texas at Austin-led team has reconstructed the most detailed map to date of the molecular machines that carried out the func
A University of Texas at Austin-led team has reconstructed the most detailed map to date of the molecular machines that carried out the functions of life in an ancient ancestor that gave rise to all complex life on Earth, including us, shedding new light on genetic causes of human diseases. This representation of protein networks, known as the protein interactome and published in Cell Genomics, is like a treasure map the researchers have used to dig up hundreds of genes that weren't previously known to be associated with human diseases. Using animal models and human patient data, they have already confirmed for the first time that three of these genes are connected to rare disorders. The work could potentially lead to new targets for treating a host of other diseases.
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