#trypanosoma

[wikipediapictures]

African trypanosomiasis

“Trypanosoma forms in blood smear from patient with African trypanosomiasis.” - via Wikimedia Commons

[bpod-bpod]

Tripping Up Chagas

Chagas disease is a global health threat and neglected tropical disease. It’s a tropical parasite spread mostly by insects, and the molecular mechanisms by which the parasite infects human cells are poorly understood. Researchers probing this damaging infection examined thrombospondin-1 (TSP1), a protein in our cells that mediates cell-to-cell interactions and plays a role in many essential functions. They found that cells lacking this key protein (right, compared to normal cells, left) resisted infection by the parasite Trypanosoma cruzi (green). The team revealed that the parasite activates the β-catenin signalling pathway, a molecular sequence of events crucial in species across the animal kingdom for everything from cell growth to movement. Their results suggest that during early infection, TSP1 enables some of this activity, and that overall the β-catenin pathway is a potential target for treatments or prevention tactics.

Written by Anthony Lewis

Image adapted from work by Ashutosh Arun and colleagues

Department of Microbiology, Immunology and Physiology, Meharry Medical College, Nashville, TN, USA

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in PLOS Neglected Tropical Diseases, January 2022

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[pterosauridae]

So I had an idea.

Everyone's making furry characters based 90% on mammals, then there are birdsonas, scalies, fishsonas and even bugsonas were a trend on Twitter for a while.

Idk if I've seen an anthro oc based on a microorganism, and if yes, these are extremely rare. So what about doing some mitosis and increase the number of microsonas?

This is Teo, a trypanosoma guy. I have a feeling this will be another OC I will never draw again, lmao. So sorry for this. :,)

[zirvedecamasirasangenc]

[written-nature]

Second, T. brucei gambiense cane be thought of as the "river form" of the parasite; it is endemic across central and western Africa and it causes a slowly progressing course of infection. Humans are the primary reservoir of this pathogen, but even the river form can infect a range of animal hosts.

"Plagues Upon the Earth: Disease and the Course of Human History" - Kyle Harper

[written-nature]

First, T. brucei rhodesiense can be thought of as the "savanna form" of the parasite; it is endemic across southern and eastern Africa and it causes an acute course of sleeping sickness. The savanna form is broad in its selection of hosts, infecting a wide range of animal reservoirs.

"Plagues Upon the Earth: Disease and the Course of Human History" - Kyle Harper

[fadingzipperdragongoop]

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[fadingzipperdragongoop]

Visit Original Link

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