#trypanosome

[biology-geology-beaches-india]

The Scientific Research Notes Of S. Sunkavally. Printed Part, Page 434.

Dates unclear, but certainly between. 2006-2012.

[biology-geology-beaches-india]

The Scientific Research Notes of S. Sunkavally (years: 2002-2011).

1106-1110.

[parasitologyillustrated]

The World is Always Smaller When You Travel (Part 2)

This patient had multiple possible parasitic organisms that could have been considered as a possible cause for his symptoms, considering his history of travel to Africa and South America. On the list of possibilities would certainly be malaria. There are rapid immunochromatographic assays available now that can help to rule out malaria. The BinaxNOW™ is an example of such a rapid…

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[most-definitely-human]

This is my first experience with this type of immunofluorescence and I’m really happy with how it came out! These are procyclic forms of T. brucei, a parasitic kinetoplastid that causes sleeping sickness. The procyclin glycoprotein covering the surface of the cells is immunolabelled in green and the DNA is fluorescing in blue due to DAPI, a fluorescent stain that binds strongly to adenine–thymine-rich regions in the nucleus and kinetoplast of each parasite.

[bpod-bpod]

Pore Form

These whip-tailed creatures are trypanosome parasites – responsible for causing sleeping sickness – viewed down a microscope. Fluorescent dyes have been used to pick out different parts of each single-celled organism: red marks their surface and tail, which enables them to move; blue highlights their DNA, contained in a bag-like structure called the nucleus; and green denotes tiny channels in this bag, known as nuclear pores. Built from around 30 different types of proteins – a staggering 500 protein molecules in total – these pores control the flow of chemicals into and out of the nucleus. Intriguingly, the structure of the nuclear pores is rather different in trypanosomes compared with those in animal, plant and yeast cells. While the central part of the pore is similar in all species, the outer parts of the channel are much more variable, suggesting that its roots go much further back in evolution than previously thought.

Written by Kat Arney

Image by Jeffery deGrasse

Image originally published under a Creative Commons Licence (BY 4.0)

Published in PLOS Biology, February 2016

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[crisscrosscutout]

So I made some phone cases for laughs because shutterfly seems to only have heteroromantic/2.5 kids and a dog family themed cases, which is fine because pigeons and trypanosomes are my true loves XD

[legoaztec]

I needed to take my mind off some unfortunate news... so happy valentines day from all the little guys inside!!!

Note: the Micrographs I pulled form Bing Images... I do not own them.

[mucholderthen]

LEISHMANIASIS: PROTOZOAN PARASITE INFECTING IMMUNE CELLS

Leishmania major is a species of trypanosomatid protozoa associated with the [human] disease zoonotic cutaneous leishmaniasis.

It is is an intracellular pathogen which infects the macrophages and dendritic cells of the immune system. It is able to survive by hiding inside immune cells, which engulf them but cannot destroy them.

Leishmania major is a major public health concern in Northern Africa, the Middle East, China, and Northwestern India.

IMAGES

L.major promastigotes [see chart] during peritoneal macrophage infection

L.major promastigotes during infection of primary fibroblast culture.

L.major amastigotes [see chart], 5 days after intracellular macrophage infection

Two rows: L.major amastigotes 5 days after infection of peritoneal mouse macrophages

Life cycle of Leishmania

Eukaryota  >  Excavata  >  Euglenozoa  >  Kinetoplastea  > Order: Trypanosomatida  >  Genus Leishmania Ross, 1903

SOURCE: Institut Pasteur and Wikipedia