I disagree with you. JK said that she regretted putting Ron and Hermione together, but that doesn't means that Ron is now useless, or some bull like that. Ron is so much more than Hermione's husband. He's Harry best friend! Like the brother he never had! So what if JK said that? It doesn't change the fact that she did indeed put them together. She saw something in them that could work. She even gave them two kids.
I think you misinterpreted me. (and I know it doesn't change the fact that she put them together. I LOVE the fact that they're together). I think the main thing that people are upset with her about (other than the fact that she clearly, in that interview, put more emphasis on Hermione's love life than all the amazing stuff Hermione has done on her own and the fact that JK can't seem to stay out of the damn media by pandering to us and adding unnecessary things to the books that are over) is that Ron get screwed over for seven books. I mean really.
He's the youngest of six boys, his family (while wonderful people) are too poor to get Ron anything that is truly his. He lives his entire life in his brothers' shadows and then when he gets to Hogwarts, he lives in Harry's shadow. That's awful. He's no good in classes, he's no good at Quidditch until Harry gives him confidence, no girl sees him when he's by Harry except for Lavender Brown (who is fucking crazy).... He has no identity of his own outside of being a Weasley and being (as you said) Harry Potter's best friend.
So he finally ends up with Hermione! The one girl he's cared about all these years, despite (or perhaps in spite?) of how they bicker! He finally has someone in his life who cares about him in such a way! He's his own person. He figures out how to destroy the horcruxes (with the basilisk fangs left in the Chamber of Secrets), he figures out how to break into the damn Chamber itself by somehow remembering a piece of parseltongue that he heard maybe once, five years before that. He's finally a hero outside of the fact that he's had Harry's back since he was 11. Which is awesome.
No, if Ron didn't end up with Hermione, that would not negate the fact that Ron Motherfucking Weasley, Our King, is a hero. But it would negate Ron's personal victory in winning the love and affection of an amazing, brilliant, and strong girl who also happens to be his best friend. Harry and Hermione ending up together, however, would perpetuate the (overdone and frustrating) story trope that the main male protagonist and the main female protagonist have to end up together. And the fact that that didn't happen in Harry Potter is yet another reason why those books/movies are amazing.