Nucleus of galaxy Centaurus A.
Credit: E J Schreier and NASA
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Nucleus of galaxy Centaurus A.
Credit: E J Schreier and NASA
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The cytoskeleton in depth The actin cytoskeleton is a network of protein fibers inside cells that helps them grow and serves as tracks to transport cargo. To investigate how small molecules interact with the actin cytoskeleton, Paul Jarman at the University of Sheffield got human cells to express fluorescent versions of the actin protein. He then collected images of the cells at different depths using a laser scanning microscope and artificially colored the actin cytoskeleton in each image. Here the bottom slices are shown in blue, the middle slices in yellow, and the top slices in red. Submitted by Paul Jarman
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Image of the Week - October 16, 2017
CIL:41685 - http://www.cellimagelibrary.org/images/41685
Description: Single slice confocal images representing one optical slice of a cell stained for the Human Protein Atlas (HPA) antibody HPA021616 (shown in green). HPA021616 is a polyclonal anti-EZR antibody that labels plasma membrane and nucleoli. The cells are also stained with reference markers in order to facilitate the annotation of the subcellular distribution of the protein targeted by the HPA antibody. The following probes/organelles are used as references; (i) DAPI for the nucleus (blue) and (ii) anti-tubulin antibody as internal control and marker of microtubules (red).
Authors: M. Uhlen, P. Oksvold, L. Fagerberg, E. Lundberg, K. Jonasson, M. Forsberg, M. Zwahlen, C. Kampf, K. Wester, S. Hober, H. Wernerus, L. Björling, and F. Ponten.
Licensing: Attribution Non-Commercial Share Alike: This image is licensed under a Creative Commons Attribution, Non-Commercial, Share Alike License.
hanging high by holding onto gravity on Flickr.
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page 131 of “A treatise on orthopedic surgery” (1910)
Today, 12 October, is Stem Cell Awareness Day and in celebration of the day, we’re taking a look at the strides that have been taken in the field of gerontology under stem cell research. Though stem cell research did not begin until 1981 when scientists discovered ways to derive embryonic stem cells from early mouse embryos, it was over fifty years ago that researchers first found that old age is associated with depletion and loss of function of stem cells. Since then, great leaps and bounds have been made in approaching stem cells and their effect on aging including hundreds of early-phase clinical trials using mesenchymal stem cells.
Image: Stem Cell by PublicDomainPictures. CC0 public domain via Pixabay.