David Shores said, "I love that we started the series with House and Wilson, and we ended it with House and Wilson. Ending with a non-traditional romantic story is atypical, and that exploration of male friendship is something you don’t see on TV very often. You see a lot of wingmen giving each other crap, and House most certainly did that. But, the idea of guys giving each other crap who loved each other was new."
This is the same interview that Hugh Laurie said, "Way before this idiot word “bromance” was coined—I wish people wouldn’t jam words together like that, there are enough words—I think it’s true that there was a great sort of weird romantic love between House and Wilson. I suppose that was the show’s central core relationship, and it was irresistible to me. I certainly did grow… I’d stop short of saying romantically involved with Robert Sean Leonard, but we became very close and enjoyed each other’s company. He made me laugh an indecent amount. I think the writers too enjoyed writing that relationship. Shore, in particular, had a real knack for it. There was a scene in which House has been suspended from the hospital, so he’s taken the role of the housewife in Wilson’s apartment. Wilson gets home one day, and House has got a basket of laundry, and he says something like, “Your shirts aren’t dry yet, but you’ve got plenty of underwear.” Shore changed the line to “We’ve got plenty of underwear,” in what I thought was one of the funniest rewrites you could possibly have in the smallest number of letters."
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