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DNA-based Medical Beauty

With the development of society, people are becoming more and more concerned about appearance and body type. The medical beauty industry came into being and developed rapidly. The application of DNA technology in the medical beauty industry is becoming more and more common. Firstly, genetic testing related to skin conditions and obesity is more and more popular. According to the test results, the obesity type and skin condition can be known clearly, and the appearance and body shape problems can be solved in a targeted manner, which can help doctors provide the exclusive customization of skincare medical beauty products for beauty lovers. Secondly, mass production of a series of protein beauty products can be achieved through genetic modification technology.

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Gene Editing Based on htDNA-chip®

The silicon-based htDNA-chip® technology platform can firstly customize the construction of gRNA libraries. Due to the flexibility of the htDNA-chip®, you can construct gRNA libraries with any performance and size. htDNA-chip® provides next-generation high-throughput sequencing analysis throughout the entire process to ensure the accuracy of each step of the synthesis. In addition, next-generation high-throughput sequencing can also be used to identify and verify the results of gene editing. Through the htDNA-chip® technology platform, cost, time and manpower will be greatly saved.

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Small Nucleic Acid Drugs

Nowadays, small nucleic acid drugs show great potential in healthcare, mainly including small interfering RNA (siRNA) drugs and microRNA (miRNA) drugs. Small nucleic acid drugs start treatment from the gene level. Its biggest advantage is that it only needs to develop sequences suitable for small nucleic acid drugs. This method avoids blindness in the drug development process. After determining the target sequence of small nucleic acid drugs, the drug development process is faster.

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Recombinant Antibodies

The antibody refers to an immunoglobulin produced by the body under the stimulation of antigenic substances. It can combine with bacteria, viruses, mycins, and other substances to play a role in preventing and treating diseases.

Through gene recombination technology, the antibody gene is processed, transformed, and reassembled. After transfection with appropriate recipient cells, the tailor-made antibody molecules are expressed. These antibody molecules modified by antibody engineering methods are new types of antibody molecules, which can retain (or increase) the specificity and main biological activity of natural antibodies, remove (or replace) irrelevant structures. Therefore recombinant antibodies are more promising than natural antibodies.

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Nuelic Acid Vaccines Based on htDNA-chip®

The function of the nucleic acid vaccines is to directly introduce the viral gene fragments (DNA or RNA) encoding a certain antigen protein into animal cells and produce the antigen protein through the protein synthesis system of the host cell. So that the foreign gene can be expressed in the animal cell. Nucleic acid vaccines aim to inject naked nucleic acid codes of specific components of pathogenic microorganisms directly into the body. These vaccines are currently developed around the world including malaria, influenza, rotavirus, HIV, and so on.

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Genetically Engineered Bacterias Drugs

Genetically engineered drugs refer to a series of biological products with biological activity that are developed through recombinant DNA technology combined with modern biotechnology such as fermentation engineering, cell engineering, and enzyme engineering to prevent and treat major human diseases. Genetically engineered drugs mainly include recombinant antibodies, nucleic acid vaccines, protein drugs and antibiotics.

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DNA-encoded Compound Library in New Drugs Research

DNA-encoded chemical library technology is increasingly being used for lead compound screening to accelerate the development of new drugs. It uses DNA fragments as barcodes to record the structural information of compounds. In a compound library containing hundreds of millions of chemical molecules, each molecule is linked to a unique piece of DNA.

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DNA-based Therapy

DNA-based drug development and production are playing an increasingly important role in modern medicine. The application of DNA-based therapy mainly includes a DNA-encoded compound library for new drugs research, genetically engineered bacterias drugs, nuelic acid vaccines, recombinant antibodies, small nucleic acid drugs, and gene editing.

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What are the applications of htDNA-chip® in healthcare?

The medical applications of htDNA-chip® mainly include DNA-based testing, DNA-based therapy, and DNA-based medical beauty. The rapid gene testing is mainly through high-throughput next-generation sequencing of htDNA-chip®. In terms of the DNA-based therapy, htDNA-chip® mainly promotes the development of various drugs. As for the medical beauty, compared with traditional medical aesthetics, htDNA-chip® has more obvious advantages which include more targeted and fewer side effects.

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Library Preparation Based on htDNA-chip

The high-throughput silicon-based htDNA-chip® technology platform can synthesize large amounts of DNA with high efficiency and high fidelity in one run, and can be used for the preparation and construction of various gene libraries.

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Next-Generation Sequencing Based on htDNA-chip®

htDNA-chip® can help prepare next-generation sequencing libraries quickly and efficiently, covering the whole-genome sequencing, RNA sequencing, targeted sequencing, exome sequencing, microbial sequencing, mitochondrial sequencing and so on.

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Gene Synthesis Based on htDNA-chip®

htDNA-chip® technology platform can synthesize thousands of genes in one run, and synthesize the target genes you need for you. Because htDNA-chip® is scalable, high-precision oligonucleotide production can achieve high-quality DNA synthesis and assembly to meet all your DNA synthesis needs.

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Oligo Pools Based on htDNA-chip®

The htDNA-chip® technology platform enables exclusive oligo pools customization, which enables simultaneous synthesis of millions of oligonucleotide sequences on a silicon-based chip in a single run. The resulting oligo pools are chemically cleaved and dissolved in tubules, and the final product is delivered to the customer as a pool of single nucleotides in the tubules.

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htDNA-chip in biological research

The silicon-based high-precision DNA synthesis htDNA chip® platform can generate higher quality genes because of significantly improved throughput and scalability.

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Applications of htDNA-chip Platform

Nowadays, DNA-related biotechnology has been more and more widely used in people's daily life, bringing convenience to people and solving a series of problems. For example, these aspects include the update of biological research tools, the development of new medical drugs and methods, the cultivation of genetically modified species, the new storage methods of data, the healthy development of the food industry, and the clean production of industrial chemicals. In order to better solve these problems, firstly it is necessary to make a huge improvement in the way of DNA synthesis. Only by synthesizing genes with high efficiency can we better promote the wider applications of DNA. The htDNA-chip® technology platform can synthesize DNA with high throughput and high fidelity, which can tap the application potential of DNA and promote the wider applications of DNA.

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htDNA-chip® Platform

Scientists developed htDNA-chip®, a high-throughput DNA synthesis technology platform based on semiconductor silicon chips. htDNA-chip® greatly reduces the volume of the DNA synthesis process compared to traditional methods, while increasing the throughput by 1,000 times. Up to 9,600 genes can be synthesized on a small single silicon chip, and the resulting DNA is orders of magnitude more accurate.