Edward Tobinick - Tumblr Blog

As founder of the Institute of Neurological Recovery (INR), Dr. Edward Tobinick created an innovative practice dedicated to the treatment of patients with various conditions related to neuroinflammation, including sciatica and other forms of intractable intervertebral disc-related pain, Alzheimer’s disease, stroke, and traumatic brain injury. At the INR since 2001, Dr. Edward Tobinick invented an array of off-label, patented medical treatment therapies that selectively target and inhibit tumor necrosis factor(TNF). Widely recognized for his clinical research, Dr. Tobinick has published numerous articles on his findings in recent years, sharing his work in peer-reviewed journals, including CNS Drugs, Current Alzheimer’s Research, and Drug Discovery Today. In addition, he has been a member of the editorial board of the Journal of Neuroinflammation and an invited ad hoc reviewer for multiple neuroscience journals. Board-certified in dermatology and internal medicine, Dr. Tobinick has spent more than 30 years teaching, practicing, and researching various fields of medicine. A former assistant clinical professor of medicine at UCLA, Dr. Tobinick also completed his residencies in dermatology and internal medicine at this school. He earned degrees from the UC San Diego School of Medicine and Brandeis University.

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U.S. Patent for Specific Cytokine Antagonists Usage

The founder of the Institute of Neurological Recovery, Dr. Edward Tobinick holds a bachelor of arts in biology from Brandeis University in Waltham, Massachusetts, and a medical degree from the University of California, San Diego School of Medicine in La Jolla, California. Over the course of his career, he has filed for a number of United States patents that cover a range of proprietary medical treatments and techniques. The U.S. Patent and Trademark Office approved Dr. Edward Tobinick’s most recent patent on January 8, 2013. Issued under the publication number US8349323 B2, this patent involves the use of cytokine antagonists for neurological and neuropsychiatric disorders. The patent details a procedure by which cytokine antagonist medication can be administered locally for the treatment of localized clinical disorders. This medication will then diffuse through capillary, venous, arterial, and lymphatic networks to reach the anatomic site of pathology or enter the patient’s cerebrospinal fluid. According to Dr. Tobinick, the modalities described in U.S. Patent US8349323 B2 have proven effective in reducing lumbar and cervical radiculopathy as well as other forms of neuropathic pain that are commonly caused by vertebral disc disease. Such localized administration of biologics offers potential benefits that range from greater efficacy and a longer duration of action to an overall reduction in side effects.

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Sciatica Treatment at The Institute of Neurological Recovery

A graduate of the University of California, San Diego School of Medicine, Dr. Edward Tobinick is the founder of the Institute of Neurological Recovery (INR) in Los Angeles and Boca Raton, Florida. Dr. Edward Tobinick and additional INR physicians implement breakthrough treatments for a variety of conditions such as sciatica. Dr. Tobinick and his colleagues were the first to publish clinical evidence of the effectiveness of etanercept used off-label for treatment of intractable intervertebral disc-related pain. Sciatica is marked by pain that radiates from the lower back or upper leg, often reaching down below the knee. Patients typically experience pain that is isolated on one side of the body and is often worse while sitting. Additional symptoms may include a burning or tingling sensation in the leg, weakness or numbness in the leg or foot, or sharp pains that hinder standing or walking. The severity of sciatica pain varies among individuals, ranging from mild irritation to incapacitating discomfort. The condition is caused by inflammation of the lumbar nerve roots. The lumbar nerve roots can be inflamed by numerous conditions including herniated discs and degenerative disc disease. At the INR, physicians treat sciatica via a noninvasive treatment that does not require anesthesia. For more information, please visit www.painbreakthrough.com.                            

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Paper Outlines Exciting Neurological Therapy

A review article authored by Dr. Edward Tobinick explores a drug called etanercept and its ability to treat certain conditions associated with an excess of an immune signaling molecule called TNF. The molecule is present in small quantities in healthy human beings, because when present in normal concentration it serves normal physiological functions, including modulation of normal synaptic function. However, if TNF begins to aggregate in excess quantity in the brain, it may exacerbate certain inflammatory neurological conditions, ranging from traumatic brain injury to Alzheimer's disease. Dr. Edward Tobinick's study especially focuses on an innovative etanercept delivery method called perispinal administration. This delivery method is designed to introduce etanercept directly into the cerebrospinal fluid and cerebrospinal venous system. Further, perispinal administration is designed to provide selective delivery to the CNS. The researcher also explores the clinical effects and scientific rationale of this off-label therapy in his article. The paper appeared as "Perispinal Etanercept: A New Therapeutic Paradigm in Neurology" in the journal Expert Review of Neurotherapeutics. Interested parties can learn more about Dr. Tobinick's groundbreaking etanercept research by logging on to the Institute of Neurological Recovery website at www.nrimed.com.

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Etancercept and Sciatica

A medical researcher and founder of the Institute of Neurological Recovery, Dr. Edward Tobinick explores the therapeutic applications of etanercept as it relates to patients impacted by sciatica and other conditions. Sciatica may appear when a herniated disc releases an inflammatory molecule, TNF, that adversely affects the spinal nerve roots, causing pain that most often manifests as pain radiating down one leg. To address sciatica, Dr. Edward Tobinick performed research on etanercept, a drug that helps patients with rheumatoid arthritis by reducing inflammation. It does so by inhibiting the action of TNF, a protein active in producing and enhancing the inflammatory response. Rheumatoid arthritis, like sciatica, may involve TNF-mediated inflammation. Therefore, etanercept may be an effective therapy for both conditions.  Since Dr. Tobinick completed his initial research on etanercept and sciatica, follow-up studies have confirmed the drug's ability to help people with this condition. Research published in recent years by scientific journals like Spine and The Open Spine Journal demonstrate that etanercept may effectively treat sciatica and other conditions that give rise to disc-related pain.

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Potential Warning Signs of a Stroke

Dr. Edward Tobinick, founder of the Institute of Neurological Recovery, first became certified by the American Board of Internal Medicine in 1980 and the American Board of Dermatology in 1982. Dr. Edward Tobinick has treated numerous patients who have suffered a stroke. Every 40 seconds someone in the world is the victim of a stroke, one of the most common neurological afflictions. While a stroke can happen at any moment, some of the symptoms may occur gradually. A stroke is often accompanied by a sensation of numbness in the body, particularly in the face or an extremity. Numbness is generally localized when associated with a stroke, affecting one side of the body. Sudden confusion is another potential warning sign of a stroke and is likely to be noticed by another person. This confusion can result in slurred or nonsensical speech and an inability to understand simple conversation. Additional symptoms of a stroke may include dizziness, problems with vision, and loss of balance.                            

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The American Board of Internal Medicine Certification

As the founder of the Institute of Neurological Recovery, Dr. Edward Tobinick conducts research and trains physicians in neurological treatment techniques. Dr. Edward Tobinick is licensed to practice medicine in California and Florida, and he is certified as a physician by the American Board of Internal Medicine. Led by physicians, the American Board of Internal Medicine is a nonprofit organization created to ensure the quality of patient care and the integrity of the medical profession. About 25 percent of physicians in America have obtained certification from the board, and there are currently over 200,000 certified doctors. The American Board of Internal Medicine recognizes 20 subspecialties, including occupation-specific medical specialties such as sports medicine, age-specific medical specialties such as adolescent medicine and geriatric medicine, and condition-specific specialties such as medical oncology and endocrinology. The American Board of Internal Medicine itself is part of the American Board of Medical Specialties, a larger organization that includes 23 other specialty boards.