I want a good heart. I want it to be made of good stuff. @lilithserenada - Tumblr Blog

weloveshortvideos

wait for the end ohmygawd

lilbitwhit-deactivated20151027

I’m am fucking screaming all cheerleaders fucking love Ke$ha

shezasag

Im the one falling through the sunroof

ezroxy-deactivated20160918

The one on the front left: Cancer, Pisces The one on the front right: Taurus, Capricorn The one in the back left: Sagittarius, Scorpio The one in the back right: Libra, Aries The one behind the window on the left: Gemini, Virgo The one falling through the sunroof: Leo, Aquarius

#i want to be these girls #all of them

whatsnew-lgbtq

Spotted in Brighton

#graffiti #queer #queer graffiti #who even knows what my tags are anymore i give up

rarecultcinema

Vampyros Lesbos (1971)

hmmmmm

@explainingthejoke ?

The image is two tweets by the same Twitter user. They say:

huh it’s funny how the bacon flavored everything trend never drew as much ire as pumpkin spice wonder why that is hmm hard to say

despite being around for much longer and reaching a more extreme saturation point hm… what could it be…

The user is discussing the different sociocultural responses two similar food trends had. While “bacon” was widely accepted and popularized, “pumpkin spice” was mocked and built into a representation of skewed priorities, wasteful spending, and lack of creative thought. The user is angry about the disparity in reputation between the two fads and is using sarcasm to bring attention to the subject.

The user is saying the difference is that the “bacon” trend was largely masculine, while the “pumpkin spice” trend was largely feminine. They are saying it is a form of subtle sexism. This isn’t a joke, it is social commentary.

tails-nightmare

ariasune

nothing has captured the feeling of owning a cat so fully as realfield

first of all amelia shepherd deserves better than owen hunt so jot that down

#grey's anatomy #amelia shepard #owen hunt

thenumberfives

i still cant believe they havent taken down the shirt i put it up there last friday im crying

ondoinganevildeedblues

#dril #again

lesbianvelmakelly

the only times in my life i ever feel useful & important & needed as a person is when i say “uhhhh i mean i have spotify premium so we can use my phone”

#fuckin same #music

thebuppiediaries

auntbutch

First Gay and Lesbian Pride Parade in Johannesburg, 1990 (displayed at the Apartheid Museum)

#lgbt #queer

7172626728388918928292991972-de

uwahh…!!! *magical girl transformation but instead i turn into a dead body*

jasper-rolls

this is the anime version of this dril tweet

whatmountains

TRANS WOMEN: HERE'S SOME SHIT YOUR DOCTOR WONT TELL YOU ABOUT HRT

1. Progesterone: not for everyone, but for many people it may increase sex drive and WILL make your boobs bigger. Also effects mood in ways that many find positive (but some find negative). Most doctors won’t prescribe this to you unless you ask. Most trans girls I know swear by it.

2. Injectible estrogen: is more effective than pill or patch form. Get on it if you can bear needles bc you will see more effects more quickly.

3. Estradiol Cypionate: There is currently a shortage of injectible estradiol valerate. There is no shortage of estradiol cypionate. Functionally they do the same shit.

4. Bicalutamide: This is an anti-androgen that has almost none of the side-effects of spironolactone or finasteride. The girls I know who are on it are evangelical about it.

naidje-deactivated

@euryale-dreams

joyeuse-noelle

Are there HRT medications that don’t increase blood clot risk? I’m already at risk because of my blood pressure, and my doctor won’t prescribe HRT that increases clot risk while I’m on the medication - and I may never not be on the medication.

euryale-dreams-deactivated20201

Absolutely.

The concerns surrounding venous thromboembolic events as a side-effect of hormone replacement therapy can mostly be traced back to one particular study known as the Women’s Health Initiative. This study was an enormous undertaking which, unfortunately, demonstrated significant adverse effects of the hormone therapies studied. As a result of this the use of hormone replacement therapy in postmenopausal cis women was dramatically reduced as the medical community began to question whether or not the therapy caused more harm than good.

Naturally, trans women have been suffering from this fall-out ever since.

What physicians seem to fail to recognize is that the study examined a very specific hormone regimen which was, arguably, outmoded at the time the study was conducted: It examined the use of conjugated equine estrogen (Premarin) with or without the use of medroxyprogesterone acetate. Neither of these drugs is regularly used for the treatment of transgender women.

The estrogen most commonly used to treat transgender women nowadays is 17β-estradiol either in pill form or in the form of a sticky patch that you apply to your skin. Esters of estrogen (e.g. estradiol valerate) are also sometimes used either in a pill form or as an intramuscular injection.

Transdermal estradiol patches are the gold standard when it comes to treating women who are at high risk of a venous thromboembolic event. It simply does not increase the risk of developing a venous thromboembolism. The only thing you should keep in mind is that patches are not always well tolerated because of the lifestyle changes required to keep them from falling off and the fact that they tend to irritate the skin.

Fortunately, oral 17β-estradiol appears to be safe, regardless of the increased risk. At least one large study has shown that the use of oral estradiol in trans women is not associated with venous thromboembolic events. An individual woman’s risk would need to be substantial in order to contraindicate the use of oral estradiol.

For those who have significant risk of venous thromboembolism because they have had a previous thromboembolic event, because they are paralyzed, or because of some other factor it is good to know the relative risk between oral and transdermal estrogen. The latest research indicates that the use of transdermal estrogen lowers your risk of a thromboembolism to 80% of what your risk would be using oral estrogens.

It’s difficult to find hard numbers regarding the relative risk of venous thromboembolic events with regards to hypertension. The best I could find after an hour or so of searching was this study regarding VTE in lung cancer patients. Hypertension increased the risk by a factor of 1.8.

However, to put that into perspective being of African descent increases your relative risk for deep vein thrombosis by a factor of 1.3 when compared to Europeans. Europeans are, themselves, at increased risk when compared to Asians and Pacific Islanders by a considerable margin: a four-fold increase.

I should point out that being ‘male’ is also a risk factor for developing a thromboembolism and hormones are likely to be a contributing factor. Also, menopause is another serious risk factor. Given this information it is likely that the use of transdermal estradiol will lower your risk of thromboembolic events significantly.

As far as the anti-androgen is concerned: The primary use for spironolactone for cisgender people is as an antihypertensive.

Even if the risk of thromboembolism was truly significant with modern hormone replacement therapy it wouldn’t justify what your doctor is doing to you. The fact is that mortality in the transgender community from suicide–caused in part due to the lack of access to hormone therapy–is substantial. The quality of life lost when a trans woman is denied hormone therapy is substantial. The fact that your doctor does not appear to be taking this into consideration when they weigh the risk of thromboembolism against not receiving necessary medical care is deeply concerning.

I strongly recommend that you seek a doctor who is more sensitive to your medical needs as a transgender woman.

Edit: Fixed a minor, but embarrassing, error.

whatmountains

oh wow this is so helpful & good info