Handsome Pixel Mullet Man *:・゚✧
macklin celebrini has autism

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Lint Roller? I Barely Know Her
YOU ARE THE REASON
Cosmic Funnies
$LAYYYTER
Xuebing Du
Jules of Nature
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Three Goblin Art
DEAR READER
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we're not kids anymore.
One Nice Bug Per Day
I'd rather be in outer space 🛸
ojovivo
noise dept.

@theartofmadeline

izzy's playlists!

shark vs the universe
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@luthientenor
Handsome Pixel Mullet Man *:・゚✧
are you guys hearing about this dude working to developing a vaccine for cats that he's hoping would like. theoretically double their lifespans?
turns out i wasn't making that up, his name is Dr. Toru Miyazaki! he also wrote a book called "The Day Cats Live To Be Thirty", so cats are kind of his thing.
apparently, cats' kidneys tend to be the thing that takes them down, something about their bodies being unable to self-clean their kidneys, and the vaccine is supposed revitalize the body's ability to do just that. It would be very VERY fucking cool to have cats suddenly reaching 30 years of age be the normal thing.
As they age, almost all cats develop kidney disease, from which they eventually die. Just as in humans, kidney disease i
Dr. Toru Miyazaki’s AIM injection for cat kidney disease enters trials in 2025, aiming for a 2027 release. Greycoat Research supports the sc
whoa wait i actually read the articles and it's so much cooler than just that!!
dude cracked the case about WHY kidneys fail, across the board as far as i can tell. turns out there's a specific molecule whose job it is to attach to waste and signal macrophages to come eat it. it remains inactive in cats for some reason, but the molecule is still there. basically what he's done is found the switch to activate them. this will be profound not only for our domestic babies, but for big cats too - especially cheetahs!
although his research was focused on cats, it's already being used to develop drugs for humans too!
on top of that, since these molecules are tags for waste, this could also dramatically lower the rate of fatty liver disease, liver cancer, urinary crystals, rheumatoid arthritis, and even some neurological cases! like, they're hoping it may have an impact on parkinson's and alzheimers, but it DOES have an impact on stroke recovery. like. holy shit.
furthermore, he's insisting that the feline drug be affordable if and when it rolls out onto the market. he wants this to be something anyone can get for their cat!! idk how much sway he'll have over the human drug, but hopefully enough that it, too, won't be that expensive.
annnnnd in his research that he's still doing for the human side of things, he's found a potential link between this molecule and estrogen. in the 20,000 samples he's tested, women between ages 10 and 29 had the highest amount of this molecule present in their blood (a higher amount means Something Fucky is going on, essentially. There's a higher amount of waste the body is trying to clean out) but it drops down to be almost equal amongst men and women after menopause. it hasn't been looked into yet, but fuck, just the fact it's noted and known and probably WILL be looked into soon??? imagine if this is what leads to figuring out all the various ways the ovaries and uterus fucks with people and how to fix it. or even like, maybe there's something about estrogen that makes it work better. who knows! but it's rad the link is there to be researched :D
man just think, not only could our kitties start living longer, healthier lives, but just maybe dialysis will become as rare and obsolete as the iron lung is for people. what a badass Dr. Toru is!
"But I don't want to turn people into dinosaurs. I wanna cure kittie kidneys!"
Update: So they have done clinical trials and have submitted it for approval as of april 2026. They are expecting it to be available late 2026/early 2027
The AIM protein drug for feline chronic kidney disease has been submitted for approval in Japan (April 2026). We break down clinical trial d
As for the study itself, the 360 day follow up on stage 3 kidney failure kitties showed that the control had a survival rate of about 20%, while the test group had a survival rate of 80%
New 2026 study: AIM protein boosts cat kidney disease survival from 20% to 80%. Discover how this scientific breakthrough is changing the fu
Our cat Scout is in the early stages of kidney disease. This might be available in time to save her!
Haven’t had a chance to watch the tutorial yet, but I’m seriously considering making this for my gf’s niece
JULY 4 , 2026
TFW you accidentally come up with your enemies' new theme song.
This comic was so rushed lol. Hope any of you fellow yankees had a happy and safe 4th of July.
Extremely funny.
i love explaining the etymology of the word "rickroll" because the story starts with "ok, so at one point 4chan applied a filter to everyone's posts that changed the word egg to duck"
grandfather....
Behind the scenes of PROJECT HAIL MARY (2026)
Has this been done yet or…
HAPPY 250TH BIRTHDAY, AMERICA!!!!
i gave my sister $100 for her bday, but i gave it to her in $1 bills that i folded into origami. so that’s how she pays for delivery food & now the pizza girl thinks she’s a stripper
You’re really good at origami holy sh
i learned it specifically to make these for this exact situation
Aren’t you the same bitch that gave your sister $100 dollars in nickels?
same bitch
Yeah, neither of these things happened 👍🏼
listen here my good hoe, i can’t find photos of the 2000 nickels or the 20 stars, but i did not spend weeks planning meticulously inconvenient birthday gifts over a period of years just to get whaled on by internet gremlins. here is some equally compelling evidence for an anecdote i was saving for later:
it weighed 68.6 lbs
same hellion yes
one of the reasons why Columbo is so funny is because he will get on his suspect's nerves sooo badly and then the suspect cannot do anything about it because Columbo will go "I'm just a little guy and it's my birthday! I'm just a little birthday boy!" with the suspect and Columbo both knowing full well that Columbo is lying but the suspect cannot say a word about it not being Columbo's birthday due to the social conventions surrounding them and the fact that they are indeed guilty of murder
This might seem like me betraying you, but this is actually me believing in you.
i can't get over this. this is fucking killing me
I have almost forgotten to post this
Still learning how to work the markers
"But when a long train of abuses and usurpations, pursuing invariably the same Object evinces a design to reduce them under absolute Despotism, it is their right, it is their duty, to throw off such Government, and to provide new Guards for their future security."
-- Declaration Of Independence
You ARE lost, my bus friend. That is a BC Transit bus and a bus stop in Vancouver, the one (1) city in the province whose transit system isn't part of BC Transit.
I am the harbinger of good vibes and nice times
PHIA SABAN as QUEEN HELAENA TARGARYEN House of the Dragon | 3x02 - "Queen's Landing" (2026)