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“The depth of the lows is the price you pay for the height of the highs.”
— Adam Kay, This is Going to Hurt: Secret Diaries of a Junior Doctor
Physiological process leading to muscle contraction
done in Adobe Illustrator
“The fact that the clock’s hands aren’t moving isn’t good news. It’s an expression of grave concern about how the global situation remains largely the same. The last time the clock was this close to midnight was in 1983—the height of the Cold War.”
— Lawrence M. Krauss on the status of the Doomsday Clock (via newyorker)
Intriguing Ritual Burial Found From Pre-Classic Mexico
Found in southern Mexico City, it is a burial unlike any other we know of. Ten interlocking skeletons of various ages and genders were laid to rest, arranged in a spiral shape. Some hold ceramic spheres and stones in their hands and the grave also contains various sizes of ceramic vessels, that presumably once contained grave goods. It is the largest single burial from the Valley of Mexico.
Laid to rest in a pit about 6 feet (2 meters) wide, they were most likely interred at the same time, sometimes between 500 and 400 BCE. Archaeologists think they were buried at the same time because the arms of one person were placed under the spine of another, suggesting they were deliberately arranged. Plus, that spiral.
So far, three of the ten remains have been sexed: two women, one man. There also appears to be a range of ages. While most on first analysis are young adults, there is at least one more mature adult, a child between 3 and 5 years old, and an infant just a few months old. Some of the skeletons, though not all, also show cranial deformations and dental mutilations, which are known to have been practiced in other Mesoamerican cultures including the Maya and Inca.
The world's second-oldest operating theater is a pink arena
There is a quite big fish on display in the Department of Animal Biology at the University of Antananarivo.
Thank you for sharing. This fish is oddly calming to me. (Despite being a lil’ grotesque)
An Explanation of Why Yankee Doodle Called the Feather in His Hat ‘Macaroni’
Michele De Lucchi - Conversion of Manica Lunga, a 15th century monastery space, to an art library, Venice 2009. Photos © Alessandra Chemollo.
The fact that the clock’s hands aren’t moving isn’t good news. It’s an expression of grave concern about how the global situation remains largely the same. The last time the clock was this close to midnight was in 1983—the height of the Cold War.
Lawrence M. Krauss on the status of the Doomsday Clock (via newyorker)
Brain differences in premature babies who later develop autism
Extremely premature babies run a much higher risk of developing autism in later childhood, and even during the neonate period differences are seen in the brains of those who do. This according to a new study by researchers from Karolinska Institutet and Karolinska University Hospital in Sweden. The findings, which are published in the journal Cerebral Cortex, suggest that environmental factors can lead to autism.
Extremely preterm neonates survive at increasingly early gestation periods thanks to the advances made in intensive care in the past decades. However, babies born more than 13 weeks prematurely run a serious risk of brain damage, autism, ADHD and learning difficulties. They are exposed to numerous stress factors during a period critical to brain development, and it is possible that this plays a key part in the development of autism spectrum disorder (ASD).
In this present study, the researchers examined over 100 babies who had been born extremely prematurely (i.e. before week 27, the beginning of the third trimester). With the parents’ permission they studied the growth of the babies’ brains using magnetic resonance imaging during the neonate period, and then screened the children for autistic features when they had reached the age of six.
“We were surprised by how many – almost 30 per cent – of the extremely preterm-born children had developed ASD symptoms,” says Ulrika Ådén, researcher at the Department of Women’s and Children’s Health at Karolinska Institutet and neonatologist at the Neonatology clinic at Karolinska University Hospital in Sweden. “Amongst children born after full term pregnancy, the corresponding figure is 1 per cent.”
The researchers found that it was more common in the group of children who had developed ASD for there to have been complications during the neonate period, such as surgery, than it was amongst their prematurely born peers who had not developed ASD. Already in the neonatal period, long before the children had manifested signs of autism, differences could be observed between the extremely preterm babies who went on to develop ASD and those who did not, with diminished growth of the parts of the brain involved in social contact, empathy and language acquisition – functions that are impaired in autistic children.
Autism is generally attributed to genetic factors, even if no specific autism gene has been identified. This new study supports previous findings indicating that birth weight and complications can increase the risk of autism.
“Our study shows that environmental factors can also cause autism,” says Dr Ådén. “The brain grows best in the womb, and if the developmental environment changes too early to a life in the atmosphere, it can disrupt the organisation of cerebral networks. With new therapeutic regimes to stimulate the development of such babies and avoid stress, maybe we can reduce the risk of their developing ASD.”
"The brain consumes a great amount of energy doing nothing."
There’s much about the brain we still have to discover, and one of the unanswered questions surrounding this most vital of organs is how it uses up most of its energy. The brain claims around 20 percent of the total oxygen used to fuel our bodies, yet we don’t know where most of that goes. Now an IBM researcher thinks he might have solved the mystery.
James Kozloski, who works as a computer neuroscientist at IBM’s Thomas J. Watson Research Centre, says the brain is constantly looping signals through established pathways - pathways that can be thought of as city street maps for our minds. The brain repeatedly retraces its steps through these pathways, covering three different areas of functionality: sensory (what’s currently happening), behavioural (what we can do about it), and limbic (what it means to us).
Kozloski calls this closed-loop model the “Grand Loop”, and hypothesises that these repeated cycles are the reason the brain needs so much energy, even when we’re not actively solving maths puzzles or trying to juggle. He successfully ran his hypothesis through the neural tissue simulator at IBM, which can produce an accurate model of the way neurons fire in the human brain.
The most expensive pocket watch in the world made for Marie Antoinette
This watch was originally designed by Breguet himself and has more pieces (823) than an iPhone. It’s self winding, has a minute repeater, perpetual calendar, equation of time, jumping hour, power reserve indicator, and a bimetallic thermometer – everything but MMS messaging. It took forty-four years for the original to be constructed and Breguet and Marie Antoinette both died before it was completed. Ultimately, the original watch disappeared, never to be seen again. When Swatch acquired Breguet, an Indiana Jones style quest for the watch began. When they came up short they reproduced the watch using only the images of the original. Breguet has received offers in the eight digit range, but still refuse to sell.
An Amazing Stop-Motion Paper Animation That Reconstructs 40,000 Years of London History
Jeppe Hein: Please Touch the Art in its new snow blanket.
top and bottom images: Micah Bozeman middle image: Laura Murray
Cementerio De Chichicastenango (Guatemala)
Flatland Aydin Buyuktas