LGBTQ People described the series as focusing around Catarina Claes who amasses a polyamorous bisexual harem pining for her as she tries to avoid being a villain and becomes very thoughtful. Reviewers pointed out three lesbian characters: Mary Hunt, Sophia Ascart, and Maria Campbell, all of whom have crushes on Catarina, as reviewer James Beckett of Anime News Network pointed out. In May 2020, seven of the 10 spots of a "weekly favourite couple poll" by Anime Trending featured Catarina paired with most of the characters. After the first season ended, with a "friendship ending," one reviewer calling it a "very definitive ending for Catarina and Her Polyamorous Bisexual Harem of Doom," and the series was later praised by Rebecca Silverman and Theron Martin of the Anime News Network for being well-done, and offers "a rewarding bisexual power fantasy" which Caterina is unaware of due to her dense nature. Anime - My Next Life as a Villainess: All Routes Lead to Doom! #animeedits #animefan #yuriromance #animesliceoflife #animelovers #animefantasy #animeschool #manga #mangas #mangayuri #yuriart #mynextlifeasavillainessallroutesleadtodoom #animegirl #animegirlcute #animegirls #animelover #animelove #animeseries #katarinaxmaria #animeromances #anime #animes #animefans #yurianime #yuri #yuricouple #yurigirls #animeart #animeillustration #otomegamenohametsuflagshikanaiakuyakureijounitenseishiteshimatta https://www.instagram.com/p/CILcu1mh01O/?igshid=12bbkuxh8cjb