Dec 5, 2024
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How heme gets the reins on blood coagulation: A PC of sequence needs to bind it
How heme gets the reins on blood coagulation: A PC of sequence needs to bind it
Von Goethe had his Mephistopheles say “Blood is a juice of very special kind”. And not wrongly, since miesteries keep coming out. The hemoglobin gives blood its red color and ensures that the erythrocytes (red blood cells) can bind oxygen for breathing. This is managed by the hemoglobin-bound molecule heme, which is a complex of a porphyrin molecule bearing a central iron ion. When the blood…
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