Nobel Prize recognizes scientists who laid groundwork for COVID-19 vaccines : Shots - Health News https://www.npr.org/1202941256
Hungarian-born biochemist Katalin Karikó and American immunologist Drew Weissman found that a chemical change to genetic code called mRNA el
The 2023 Nobel Prize for Physiology or Medicine has been awarded to Hungarian-born Katalin Karikó and American Drew Weissman for work that enabled the development mRNA COVID-19 vaccines. Their work, undertaken at the University of Pennsylvania, made it possible to develop vaccines based on genetic material called messenger RNA. The scientists discovered that changing a chemical building block of mRNA – substituting pseudouridine for uridine — eliminated an inflammatory side effect that was a barrier to development of this new kind of vaccine. They published their work 15 years before the COVID pandemic.
