#ecdnaborne

[dr-afsaeed]

EcDNA-borne structural variants drive oncogenic fusion transcript amplification - Research

Extrachromosomal DNA (ecDNA) is a major source of oncogenic fusions across cancer types, generating tissue-specific fusion landscapes with diagnostic potential. EcDNA-borne PVT1 5′-end fusions stabilize partner RNAs and boost oncogene output. Read more about this post… Credits: Source Disclaimer