It’s very possible that you might encounter supremely enlightened entities while tripping, especially on tryptamines such as dimethyltryptamine (DMT) and even LSD. They may also appear to be extremely powerful and even omniscient, so it’s extremely easy to see how you could become enthralled by them. The fourteenth-century*22Bardo T’ ödol warns us again and again about such Buddhas as these, telling us that, while they are, in fact, just as wise and compassionate as they seem, they are nothing but the deepest nature of ourselves, being unrecognized emanations of our own Buddha-nature. We see them as separate because of our ingrained habit of not recognizing our innate enlightened nature, and they are the reason that the Zen koan told us to kill the Buddha on the road when we met him. While this Buddha-nature is the real deal, we still insist on seeing him as other, not us; somehow different and “on the road.”
Quote from the book Psychedelic Buddhism: a User's Guide to Traditions, Symbols, and Ceremonies of Mike Crowley