DNA Polymerase I
-- first DNA polymerase discovered
-- discovered by Sylvy Levy and Arthur Kornberg
-- an enzyme
-- isolated from E. coli
-- involved in prokaryotic DNA replication
-- member of the alpha/beta protein superfamily
-- alpha-helices and beta-strands occur in irregular sequences
-- directs DNA synthesis
-- requires DNA template to read
-- requires all four deoxyribonucleoside triphosphates to grow the complementary strand
-- mediates proofreading
-- involved in DNA repair
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