#epivir

[pozmagazine]

ViiV Seeks FDA Approval for Two-Drug HIV Treatment

ViiV Healthcare has applied to the Food and Drug Administration (FDA) for approval of the two-antiretroviral single-tablet regimen of Tivicay (dolutegravir) plus Epivir (lamivudine) for the treatment of HIV.

The application is based on the results of the GEMINI 1 and 2 studies, which included more than 1,400 people with HIV who had viral loads up to 500,000 before starting treatment. Forty-eight-week results from the studies were presented at the International AIDS Conference in Amsterdam (AIDS 2018). By that decisive point in the studies, the two-drug combo was as effective as a three-drug regimen of Tivicay plus Truvada (tenofovir disoproxil fumarate/emtricitabine).

[hivforum]

Does Lamivudine has any long-term effect?

No, lamivudine (3TC) is one of the safest drugs I can think of.

[hivforum]

I've seen a few people from Brazil sending questions to you claiming to take Atripla. It might be the case I guess, but usually our first option here is actually tenofovir+lamivudine+efavirenz (single pill). Atripla has emtricitabine instead of lamivudine, right? Are emtricitabine and lamivudine similar/the same? Which one is a better option? Thank you.

There may be some advantages of emtricitabine over lamivudine, but the two drugs are quite similar and the differences are subtle. If you take your medications without missing many doses, there should be no problem with the lamivudine combination.