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Oesia
Реконструкція Oesia з гіпотетично закритими кінцевими кінцями трубок. Частина однієї трубки видалена, щоб показати самого черв’яка.
Oesia — моноспецифічний рід, відомий з середньокембрійських сланців Берджес. 1147 екземплярів Oesia відомі з шару Великих філопод, де вони складають 2,18% спільноти. Незважаючи на деяку схожість з щетинкощелепними (Chaetognatha), їхня спорідненість невідома.
Повний текст на сайті "Вимерлий світ":
https://extinctworld.in.ua/oesia/
@filopodia lmao sorta. it wasn’t like it was hidden or anything, but i’d never climbed the stairs. until i did
when i leave my apartment, just to the right is a staircase that ostensibly leads to more apartments, but instead it leads to unmarked doors behind which (when i climbed the 4-5 storeys’ worth of stairs, i discovered) always seem to be muffled dinner party background chichat noises
A terf once called me a “person with a false morality” because I said that a hysterectomy (removal of the uterus) doesn’t cause someone to go into menopause lmaoooooo (to any terfs that wanna clown on this ask, explain to me how I had a hysterectomy and how I’m not in menopause)
OOGA BOOGA YOU HAVE DISRESPECTED THE MIGHTY UTERUS
Like other coronaviruses, the virus behind COVID-19 causes infected cells to grow spindly projections that may act as highways to other cells.
Like a scene out of a sci-fi movie, cells invaded by the coronavirus can sprout probing appendages bedecked with viral bits.
Human cells infected with SARS-CoV-2, the coronavirus that causes COVID-19, formed more numerous and longer extremities, called filopodia, than uninfected cells, researchers report online June 28 in Cell. High-resolution electron microscopy confirmed the presence of these filopodia in infected monkey cells and captured SARS-CoV-2 viral particles budding from the projections. These protrusions may have unexplored roles in spreading the virus, and could serve as targets for future antiviral therapies.
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Similar spindly projections are found on some healthy cells, where the structures serve different roles. Repair cells, for example, send out filopodia to detect chemical cues to navigate to wound sites.
Other viruses, including the coronavirus behind the SARS epidemic, also can cause cells to sprout filopodia. Some viruses, such as Marburg and Ebola, travel along filopodia of infected cells and may use the structures to move directly from one cell to another.
The extensions “are highways for transport,” says Robert Grosse, a cell biologist at the University of Freiburg in Germany.
SARS-CoV-2, the virus that causes COVID-19, can cause infected cells to produce hairlike projections that extend away from their surfaces (colored white in this fluorescence microscopy image of a pair of human colon cells) that may play a role in the virus’ spread in the body. CREDIT: ROBERT GROSSE/CIBSS/UNIVERSITY OF FREIBURG
More work is needed to confirm what role filopodia play in a COVID-19 infection. Microscopy of infected cells over time would provide insight into whether these cell-to-cell connections affect viral spread, says Mark Denison, a virologist at Vanderbilt University Medical Center in Nashville not involved in the study.
The filopodia observed in the new study contained a protein called CK2. Cells dosed with silmitasertib, a CK2-inhibiting molecule in clinical trials for various cancers, were more resistant to a SARS-CoV-2 infection than untreated counterparts. That suggests that CK2 could be a target for future coronavirus drug treatments, Grosse says (SN: 3/10/20).
@filopodia replied to your post “Just got back from The Shape Of Water and I enjoyed greatly with our...”
Damn now I can’t watch the fish fucker movie
don’t worry, the person who says it is Literally The Fucking Worst, Baltimore is vindicated
Unsevered Fingers
Scratching around in the dark, filopodia poke out from growth cones like tiny fingers from a hand, helping young nerve cells (neurons) to find each other. Pictured here under a high-powered microscope, researchers zoom in on the secret of their wriggling in a rat’s neuron. Filopodia are made with a stiff protein called actin (highlighted here in green), held rigid by another protein called fascin – every now and then these fingers need renewing and are severed by a protein called cofilin (red). Yet researchers find in certain conditions cofilin wraps itself around the actin, breaking the ties with fascin and allowing filopodia to bend and flex. This gentler role for the nervous finger chopper may be crucial in helping neurons search their environment during development, and may be guided later in life in treatments for neurodegenerative disease.
Written by John Ankers
Video by Ryan K. Hylton and colleagues
Department of Biochemistry and Molecular Biology, Penn State College of Medicine, Hershey, PA, USA
Video originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
Published in Nature Communications, May 2022
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@filopodia
im imagining a single tattoo which sucks the viewer in to observe celebrations of halloween, a la “the illustrated man”
in which case a) very cool and b) you got a lady who can give me one of those? is she taking reservations? schedule me for one plz
Growing Up
Metamorphosis sees tadpoles transforming into frogs and caterpillar larvae blooming into butterflies. This fruit fly larva undergoes its own changes – here a thin layer of muscle grows along its testis, pictured under a high-powered microscope. Each developing muscle cell or myotube is followed in rainbow colours by a computer algorithm (right). This unusual living model teaches researchers more about cell migration – here myotubes use tiny finger-like filopodia to feel around and move 'upwards' into space, while movement 'downwards' is blocked by contact with other cells, giving the migrating cells direction. Analysing the genes and chemicals involved may suggest ways in which development can be guided in cells with faulty genes, perhaps raising hopes for treating human developmental conditions.
Written by John Ankers
Image adapted from work by Maik C. Bischoff and colleagues
Institute of Physiology and Pathophysiology, Department of Molecular Cell Physiology, Philipps-University, Marburg, Germany
Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
Published in Nature Communications, February 2021
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