Jul 1, 2013
Great Study: Hypersensitivities & The Importance of HLA In atopic patients, most whom had asthma, HLA-DR4 and/or HLA-DR7 alleles,"were present in 42.6% of the patients and in only 2.4% of the healthy controls. These results confirm a previous study of a group of polysensitized atopic patients, which showed that DR4 and DR7 alleles were rare in healthy control subjects and frequently observed in atopic subjects with or without concomitant asthma." (Senechal, H. et al.) (HLA-DR4 has been found to be increased in some chronic fatigue syndrome and fibromyalgia studies but not others. It was increased in a CFS cohort with evidence of viral reactivation.)